Dr. Jonathan Mccullers is a pediatric infectious disease specialist practicing in Memphis, TN. Dr. Mccullers specializes in recurring or persistent diseases caused by bacteria, parasites or fungus in infants, children and adolescents. Pediatric infectious disease specialists also provide consultation to other health care professionals dealing with complex cases.
PediatricsAmerican Board of PediatricsABP- Pediatric Infectious Diseases
- Reassortment and insertion-deletion are strategies for the evolution of influenza B viruses in nature.
- Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor.
- Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae.
- Respiratory viruses predisposing to bacterial infections: role of neuraminidase.
- Levels of total fungus and Aspergillus on a pediatric hematopoietic stem cell transplant unit.
- Effect of antiviral treatment on the outcome of secondary bacterial pneumonia after influenza.
- Multiple genotypes of influenza B virus circulated between 1979 and 2003.
- Association between tea ingestion and invasive Bacillus cereus infection among children with cancer.
- The novel parainfluenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 prevents lethal synergism between a paramyxovirus and Streptococcus pneumoniae.
- Antiviral therapy of influenza.
- A single amino acid change in the C-terminal domain of the matrix protein M1 of influenza B virus confers mouse adaptation and virulence.
- Influenza virus neuraminidase contributes to secondary bacterial pneumonia.
- Increased influenza vaccination of healthcare workers at a pediatric cancer hospital: results of a comprehensive influenza vaccination campaign.
- Live attenuated influenza vaccine is safe and immunogenic in immunocompromised ferrets.
- The clinical need for new antiviral drugs directed against influenza virus.
- Bacterial sinusitis and otitis media following influenza virus infection in ferrets.
- Insights into the interaction between influenza virus and pneumococcus.
- Distinct contributions of vaccine-induced immunoglobulin G1 (IgG1) and IgG2a antibodies to protective immunity against influenza.
- A step closer to meeting the threat of avian influenza.
- Induction of pro- and anti-inflammatory molecules in a mouse model of pneumococcal pneumonia after influenza.
- Novel strategy to prevent otitis media caused by colonizing Streptococcus
- N-linked glycosylation attenuates H3N2 influenza viruses.
- The platelet activating factor receptor is not required for exacerbation of bacterial pneumonia following influenza.
- Evolution, benefits, and shortcomings of vaccine management.
- Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia.
- FluBlok, a recombinant influenza vaccine.
- c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection.
- Live, attenuated influenza virus (LAIV) vehicles are strong inducers of immunity toward influenza B virus.
- Planning for an influenza pandemic: thinking beyond the virus.
- Vaccines against pandemic influenza: what can be done before the next pandemic?
- Preparing for the next influenza pandemic.
- Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza.
- A multi-valent vaccine approach that elicits broad immunity within an influenza subtype.
- Are toilet seats a vector for transmission of methicillin-resistant Staphylococcus aureus?
- Chloroquine is effective against influenza A virus in vitro but not in vivo.
- Use of atmospheric non-thermal plasma as a disinfectant for objects contaminated with methicillin-resistant Staphylococcus aureus.
- A practical guide to alcohol-based hand hygiene infrastructure in a resource-poor pediatric hospital.
- The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis.
- Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?
- Contribution of vaccine-induced immunity toward either the HA or the NA component of influenza viruses limits secondary bacterial complications.
- Recipients of vaccine against the 1976 "swine flu" have enhanced neutralization responses to the 2009 novel H1N1 influenza virus.
- PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology.
- Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets.
- Seroprevalence of seasonal and pandemic influenza A viruses in domestic cats.
- Glycan shielding of the influenza virus hemagglutinin contributes to immunopathology in mice.
- Influenza virus primes mice for pneumonia from Staphylococcus aureus.
- Mathematical model of a three-stage innate immune response to a pneumococcal lung infection.
- Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics.
- Immunotherapy with a combination of intravenous immune globulin and p4 peptide
- Preventing and treating secondary bacterial infections with antiviral agents.
- Safety of live attenuated influenza vaccine in mild to moderately immunocompromised children with cancer.
- Motivating factors for high rates of influenza vaccination among healthcare workers.
- Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden, in pregnant mice.
- Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza.
- Immunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82.
- Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer.
- Impaired wound healing predisposes obese mice to severe influenza virus
- Immunogenicity and safety of inactivated monovalent 2009 H1N1 influenza A vaccine
- Therapeutics against influenza.
- Correlates of vaccine protection from influenza and its complications.
- T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection.
- A single point mutation (Y89F) within the non-structural protein 1 of influenza A viruses limits epithelial cell tropism and virulence in mice.
- Risk of catheter-associated infection in young hematology/oncology patients receiving long-term peripheral nerve blocks.
- Naturally occurring swine influenza A virus PB1-F2 phenotypes that contribute to superinfection with Gram-positive respiratory pathogens.
- Do specific virus-bacteria pairings drive clinical outcomes of pneumonia?
- The age distribution of mortality due to influenza: pandemic and peri-pandemic.
- Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses.
- Kinetics of coinfection with influenza A virus and Streptococcus pneumoniae.
- Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections.
- Live attenuated influenza vaccine, but not pneumococcal conjugate vaccine, protects against increased density and duration of pneumococcal carriage after influenza infection in pneumococcal colonized mice.
- New virulence determinants contribute to the enhanced immune response and reduced virulence of an influenza A virus A/PR8/34 variant.
- A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection.
- Safety of high dose trivalent inactivated influenza vaccine in pediatric patients with acute lymphoblastic leukemia.
- Adjunctive corticosteroid therapy improves lung immunopathology and survival during severe secondary pneumococcal pneumonia in mice.
- A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media.
- The immune profile associated with acute allergic asthma accelerates clearance of influenza virus.
- Live attenuated influenza vaccine enhances colonization of Streptococcus pneumoniae and Staphylococcus aureus in mice.
- The co-pathogenesis of influenza viruses with bacteria in the lung.
- NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.
- Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens.
- The public health policy implications of understanding metabiosis.
- Secondary bacterial infections in influenza virus infection pathogenesis.
- Chronic helminth infections impair pneumococcal vaccine responses.
- Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?
- Non-avian animal reservoirs present a source of influenza A PB1-F2 proteins with novel virulence-enhancing markers.
- Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions.
- Live attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear.
- Randomized, double-blind comparison of standard-dose vs. high-dose trivalent inactivated influenza vaccine in pediatric solid organ transplant patients.
- Community-acquired pneumonia requiring hospitalization among U.S. children.
- Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway.
- Antibiotic Choice for Children Hospitalized With Pneumonia and Adherence to
- Glycosylation Analysis of Engineered H3N2 Influenza A Virus Hemagglutinins with Sequentially Added Historically Relevant Glycosylation Sites.
- Immunogenicity and safety of high-dose trivalent inactivated influenza vaccine compared to standard-dose vaccine in children and young adults with cancer or HIV infection.
- The Role of Punctuated Evolution in the Pathogenicity of Influenza Viruses.
- Association of sputum microbiota profiles with severity of community-acquired pneumonia in children.
- Antimicrobial peptides alter early immune response to influenza A virus infection in C57BL/6 mice.
- Serology Enhances Molecular Diagnosis of Respiratory Virus Infections Other than Influenza in Children and Adults Hospitalized with Community-Acquired Pneumonia.
- Glycosylation changes in the globular head of H3N2 influenza hemagglutinin modulate receptor binding without affecting virus virulence.
- Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.
- Low Retinol-Binding Protein and Vitamin D Levels Are Associated with Severe
- Candida tropicalis osteomyelitis: case report and review.
- Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice.
- University Of Al Hospital
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- Facts About Meningitis Vaccines
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- Is the MMR Vaccine Safe for My Baby?
It is natural to be concerned about whether immunization is safe for your child or not. However, doctors recommend getting children immunized because vaccines are thoroughly checked before they are licensed for use. The measles, mumps, and rubella (MMR) vaccine is the most effective way to protect...
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