Dr. C. garrison Fathman MD

Publications

• JOURL OF MOLECULAR CELL BIOLOGYReduced DEAF1 function during type 1 diabetes inhibits translation2013
• TURE REVIEWS RHEUMATOLOGYNew tools for classification and monitoring of autoimmune diseases2012
• TUREExploiting a tural conformatiol switch to engineer an interleukin-2 'superkine'2012
• JOURL OF BIOLOGICAL CHEMISTRYTherapeutic Effects of Systemic Administration of Chaperone alpha B2012
• CLINICAL IMMUNOLOGYDifferential mTOR and ERK pathway utilization by effector CD4 T cells suggests combitorial drug2012
• FEBS JOURLGRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness2011
• MOLECULAR THERAPYA Short Pulse of IL-4 Delivered by DCs Electroporated With Modified mR Can Both Prevent2010
• ture immunologyA model for harmonizing flow cytometry in clinical trials.2010
• CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITYNew technologies for autoimmune disease monitoring2010
• TURE IMMUNOLOGYDeaf1 isoforms control the expression of genes encoding peripheral tissue antigens2009
• JOURL OF IMMUNOLOGYThe Transmembrane E3 Ligase GRAIL Ubiquitites and Degrades CD83 on CD4 T Cells2009
• BLOODLymphoid tissue-specific homing of bone marrow-derived dendritic cells2009
• JOURL OF IMMUNOLOGYive CD4 T Cell Proliferation Is Controlled by Mammalian Target of Rapaiycin Regulation of GRAIL2009
• CLINICAL IMMUNOLOGYTissue- and age-specific changes in gene expression during disease induction and progression in NOD2008
• JOURL OF BIOLOGICAL CHEMISTRYThe single subunit transmembrane E3 ligase gene related to anergy in lymphocytes2008
• JOURL OF IMMUNOLOGYCutting edge: The transmembrane E3 ligase GRAIL ubiquitites the costimulatory molecule CD40 ligand2008
• CLINICAL IMMUNOLOGYTissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL2008
• JOURL OF IMMUNOLOGYive and memory T cells induce different types of graft-versus-host disease2007
• JOURL OF BIOMEDICAL OPTICSMultimodality imaging of T-cell hybridoma trafficking in collagen-induced arthritic mice2007
• TURE REVIEWS IMMUNOLOGYMolecular mechanisms of CD4(+) T-cell anergy2007
• JOURL OF IMMUNOLOGYA novel E3 ubiquitin ligase substrate screen identifies Rho guanine dissociation inhibitor as a2006
• TURE CLINICAL PRACTICE RHEUMATOLOGYDoes our current underst2006
• IMMUNITYT cell anergy: Where it's LAT2006
• TURE IMMUNOLOGYCYLD: deubiquitition-induced TCR sigling2006
• AUTOIMMUNITY REVIEWSDeveloping the concept of adoptive cellular gene therapy of rheumatoid arthritis2006
• ANNUAL REVIEW OF MEDICINECD4(+)CD25(+) regulatory T cells and their therapeutic potential2006
• BLOODL-selectin and beta(7) integrin on donor CD4 T cells are required for the early migration to host2005
• Expert review of clinical immunologyTargeted gene therapy of autoimmune diseases: advances and prospects.2005
• TRANSPLANTATIONMolecular imaging using labeled donor tissues reveals patterns of engraftment, rejection2005
• TUREAn array of possibilities for the study of autoimmunity2005
• BLOODOnly the CD62L(+) subpopulation of CD4(+)CD25(+) regulatory T cells protects from lethal acute GVHD2005
• ture MedicineProtein microarrays for multiplex alysis of sigl transduction pathways2005
• Clinical ImmunologyFostering interdiscipliry immunology2005
• TURE MEDICINEProtein microarrays for multiplex alysis of sigl transduction pathways2004
• JOURL OF IMMUNOLOGYMurine CD4(+) CD25(+) regulatory T cells fail to undergo chromatin remodeling across the proximal2004
• JOURL OF CLINICAL INVESTIGATIONGene therapy for type 1 diabetes: a novel approach for targeted treatment of autoimmunity2004
• JOURL OF IMMUNOLOGYThe gene related to anergy in lymphocytes, an E3 ubiquitin ligase2004
• TRENDS IN BIOTECHNOLOGYTargeted gene therapy: frontiers in the development of 'smart drugs'2004
• TURE IMMUNOLOGYTwo isoforms of otubain 1 regulate T cell anergy via GRAIL2004
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMCostimulatory sigls controlling regulatory T cells2003
• TURE MEDICINECD4(+)CD25(+) regulatory T cells preserve graft-versus2003
• GENE THERAPYLocalized expression of an anti-TNF single2003
• IMMUNITYGRAIL: An E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic2003
• MYASTHENIA GRAVIS AND RELATED DISORDERSTreatment of autoimmune disease by adoptive cellular gene therapy2003
• Genome biologyScratching the (T cell) surface.2003
• IMMUNOLOGIC RESEARCHT-cell anergy - From phenotype to genotype and back2003
• CIRCULATION JOURLShort polymers of arginine rapidly translocate into vascular cells2002
• CLINICAL IMMUNOLOGYRetroviral gene therapy of collagen-induced arthritis by local delivery of IL-42002
• JOURL OF ALLERGY AND CLINICAL IMMUNOLOGYCD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity2002
• CLINICAL IMMUNOLOGYThe potential for gene therapy in the treatment of autoimmune disease2002
• JOURL OF IMMUNOLOGYThe Subpopulation of CD4(+) CD25(+) splenocytes that delays adoptive transfer2002
• JOURL OF EXPERIMENTAL MEDICINEDonor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft2002
• Autoimmunity reviewsAdoptive cellular gene therapy of autoimmune disease.2002
• ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICAImmunomodulatory vaccition in autoimmune disease2002
• pharmacogenomics jourlA complicated relationship2002
• EXPERIMENTAL HEMATOLOGYBioluminescence imaging of lymphocyte trafficking in vivo2001
• CURRENT OPINION IN IMMUNOLOGYGene therapy in autoimmune disease2001
• JOURL OF IMMUNOLOGYCD4(+)CD25(+) T cells facilitate the induction of T cell anergy2001
• TURE IMMUNOLOGYAutoimmune diseases: genes, bugs and failed regulation2001
• JOURL OF IMMUNOLOGYAdoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL2001
• CLINICAL IMMUNOLOGYImmunization with D encoding an immunodomint peptide of insulin prevents diabetes in NOD mice2001
• JOURL OF CLINICAL INVESTIGATIONAntigen-specific T cell-mediated gene therapy in collagen-induced arthritis2001
• JOURL OF EXPERIMENTAL MEDICINET cell receptor (TCR)2000
• CIRCULATIONRapid and efficient vascular transport of arginine polymers inhibits myointimal hyperplasia2000
• JOURL OF PEPTIDE RESEARCHPolyarginine enters cells more efficiently than other polycationic homopolymers2000
• JOURL OF IMMUNOLOGYTargeting rare populations of murine antigen2000
• Fathman, C. G., Costa, G. L., Seroogy, C. M.Gene therapy for autoimmune disease2000
• TRANSPLANTATIONIdentification and characterization of the antigen2000
• Current directions in autoimmunityApplication of gene therapy in autoimmune disease.2000
• GENE THERAPYThe application of gene therapy in autoimmune diseases2000
• JOURL OF IMMUNOLOGYIsolation of self antigen-reactive cells from inflamed islets of nonobese diabetic mice using CD41999
• ScienceA new look at MHC and autoimmune disease.1999
• JOURL OF IMMUNOLOGYSuppressive immunization with D encoding a self-peptide prevents autoimmune disease1999
• CLINICAL IMMUNOLOGYLocal delivery of TNF by retrovirus1999
• JOURL OF EXPERIMENTAL MEDICINEAlysis of the role of variation of major histocompatibility complex cl1998
• JOURL OF EXPERIMENTAL MEDICINET cell receptor (TCR) engagement leads to activation1998
• JOURL OF IMMUNOLOGYFollowing antigen challenge1998
• JOURL OF SURGICAL RESEARCHProlongation of cardiac graft survival with anti-CD4Ig plus hCTLA4Ig in primates1998
• INTERTIOL IMMUNOLOGYRegulation of programmed cell death following T cell activation in vivo1998
• IMMUNOLOGIC RESEARCHA gene therapy approach to treatment of autoimmune disease1998
• CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGYThe association of MHC with autoimmune diseases1998
• JOURL OF AUTOIMMUNITYCD45RB(high) CD4(+) T cells from IFN-gamma knockout mice do not induce wasting disease1997
• JOURL OF IMMUNOLOGYIntroduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide1997
• Krieger, N. R., Ito, H., Fathman, C. G.Rat pancreatic islet and skin xenograft survival in CD4 and CD8 knockout mice1997
• JOURL OF EXPERIMENTAL MEDICINELocal delivery of interleukin 4 by retrovirus1997
• JOURL OF HEART AND LUNG TRANSPLANTATIONThe use of CD4 and CD8 knockout mice to study the role of T1997
• TRANSPLANTATIONInduction of tolerance to small bowel allografts in high-responder rats by combining anti1996
• JOURL OF EXPERIMENTAL MEDICINECD4(+) but not CD8(+) cells are essential for allorejection1996
• DIABETESbeta-cell destruction may be a late consequence of the autoimmune process in nonobese diabetic mice1996
• JOURL OF IMMUNOLOGYQuantitative alysis of T cell activation - Role of TCR ligand density and TCR affinity1996
• JOURL OF EXPERIMENTAL MEDICINEBreaking self-tolerance in nonobese diabetic mice1996
• Shimada, A., Charlton, B., Rohane, P., TAYLOREDWARDS, C., Fathman, C. Immune regulation in type 1 diabetes1996
• IMMUNITYMonoclol T cells identified in early NOD islet infiltrates1996
• TURETreatment of experimental encephalomyelitis with a peptide alogue of myelin basic protein1996
• DIABETESPathogenic and protective roles of CD45RB(low) CD4(+) cells correlate with cytokine profiles in the1996
• JOURL OF IMMUNOLOGYMice with a disrupted IFN1996
• Transplant immunologyTissue-specific effects of anti-CD4 therapy in induction of allograft unresponsiveness in high1995
• HOSPITAL PRACTICETERRY COMPLEX THERAPY FOR AUTOIMMUNE-DISEASE1995
• JOURL OF IMMUNOLOGYINDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN HIGH RESPONDER RATS BY COMBINING ANTI1995
• JOURL OF IMMUNOLOGYCD4-POSITIVE SUPPRESSOR CELLS BLOCK ALLOTRANSPLANT REJECTION1995
• DIABETESISLET-INFILTRATING LYMPHOCYTES FROM PREDIABETIC NOD MICE RAPIDLY TRANSFER DIABETES TO NOD-SCID1995
• CURRENT OPINION IN IMMUNOLOGYREGULATION OF AUTOIMMUNE-RESPONSE1994
• JOURL OF AUTOIMMUNITYPREVENTION OF DIABETES AND INSULITIS BY NEOTAL INTRATHYMIC ISLET ADMINISTRATION IN NOD MICE1994
• EUROPEAN JOURL OF IMMUNOLOGYCD4-POSITIVE HEAT-STABLE ANTIGEN-POSITIVE THYMOCYTES CAUSE GRAFT-VERSUS-HOST DISEASE ACROSS1994
• ADVANCES IN IMMUNOLOGY, VOLUME 56IMMUNOTHERAPEUTIC STRATEGIES DIRECTED AT THE TRIMOLECULAR COMPLEX1994
• ANNUAL REVIEW OF IMMUNOLOGYMECHANISMS OF TRANSPLANTATION TOLERANCE1994
• JOURL OF IMMUNOLOGYSELECTION FOR AMINO-ACID-SEQUENCE AND J-BETA-ELEMENT USAGE IN THE BETA-CHAIN OF DBA 2V BETA1993
• Fathman, C. G.PEPTIDES AS THERAPY OF AUTOIMMUNE-DISEASE1993
• TUREINDUCTION OF RELAPSING PARALYSIS IN EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS BY BACTERIAL1993
• TRANSPLANTATIONEVIDENCE THAT CLOL ANERGY IS INDUCED IN THYMIC MIGRANT CELLS AFTER ANTI-CD41993
• JOURL OF IMMUNOLOGYSEB INDUCED ANERGY - MODULATION OF IMMUNE1993
• TRANSPLANTATIONTHE USE OF GRANZYME A AS A MARKER OF HEART-TRANSPLANT REJECTION IN CYCLOSPORINE OR ANTI1993
• SCIENCEREQUIREMENT FOR CD8+ CELLS IN T-CELL RECEPTOR PEPTIDE-INDUCED CLOL UNRESPONSIVENESS1993
• TRANSPLANTATIONEVIDENCE THAT ANTI-CD8 ABROGATES ANTI1993
• Immunology seriesAnti-CD4 antibodies in diabetes.1993
• SCIENCEAMELIORATION OF AUTOIMMUNE ENCEPHALOMYELITIS BY MYELIN BASIC1992
• RHEUMATIC DISEASE CLINICS OF NORTH AMERICAIMMUNOTHERAPY OF RHEUMATIC DISEASES BASED ON UNDERSTANDING GENETIC PREDISPOSITION TO THE1992
• IMMUNOLOGICAL REVIEWSANTI-CD4 MONOCLOL-ANTIBODIES IN THERAPY - CREATION OF NONCLASSICAL TOLERANCE IN THE ADULT1992
• JOURL OF IMMUNOLOGYLIMITED T-CELL RECEPTOR BETA-CHAIN USAGE IN THE SPERM WHALE MYOGLOBIN 110-1211992
• jourl of rheumatology. SupplementWhat a rheumatologist needs to know about T cell receptor structure and function.1992
• JOURL OF EXPERIMENTAL MEDICINEPRESENTATION OF ANTIGEN BY MIXED ISOTYPE CLASS-II MOLECULES IN NORMAL H-2D MICE1992
• DIABETESANTI-CD8 ABROGATES EFFECT OF ANTI-CD4-MEDIATED ISLET ALLOGRAFT SURVIVAL IN RAT MODEL1991
• JOURL OF EXPERIMENTAL MEDICINEGENETIC DISSECTION OF T-CELL RECEPTOR-V-BETA GENE REQUIREMENTS FOR SPONTANEOUS MURINE DIABETES1991
• JOURL OF EXPERIMENTAL MEDICINETHE T-CELL RECEPTOR REPERTOIRE INFLUENCES V-BETA ELEMENT USAGE IN RESPONSE TO MYOGLOBIN1991
• Ruberti, G., Livingstone, A., Danska, J. S., Gaur, A., Fathman, C. G.ALYSIS OF THE TERRY COMPLEX OF ANTIGEN1991
• HUMAN IMMUNOLOGYMOLECULAR ALYSIS OF THE ROLE OF THE HLA CLASS-II GENES DRB1, DQA11991
• JOURL OF EXPERIMENTAL MEDICINEANTI-CD4 MEDIATES CLOL ANERGY DURING TRANSPLANTATION TOLERANCE INDUCTION1991
• JOURL OF IMMUNOLOGYGENETIC-ALYSIS OF DIABETES IN THE NONOBESE DIABETIC MOUSE .1. MHC AND T1991
• IMMUNOGENETICSDRB1-STAR-LY10 - A NEW DRB1 ALLELE AND ITS HAPLOTYPIC ASSOCIATION1990
• JOURL OF EXPERIMENTAL MEDICINET-CELL RECEPTOR-MEDIATED NEGATIVE SELECTION OF AUTOREACTIVE LYMPHOCYTE-T PRECURSORS OCCURS AFTER1990
• TRANSPLANTATIONINDUCTION OF DONOR-SPECIFIC UNRESPONSIVENESS TO CARDIAC ALLOGRAFTS IN RATS BY PRETRANSPLANT ANTI1990
• JOURL OF EXPERIMENTAL MEDICINETHE PRESUMPTIVE CDR3 REGIONS OF BOTH T-CELL RECEPTOR ALPHA1990
• HUMAN IMMUNOLOGYSHARED MOLECULAR MARKERS OF GENETIC PREDISPOSITION TO SEROPOSITIVE RHEUMATOID-ARTHRITIS1990
• TRANSPLANTATIONCARDIAC ALLOGRAFT PROLONGATION IN MICE TREATED WITH COMBINED POSTTRANSPLANTATION TOTAL1989
• JOURL OF EXPERIMENTAL MEDICINEA SUBSET OF MEMORY CD4+ HELPER LYMPHOCYTES-T IDENTIFIED BY EXPRESSION OF PGP-11989
• JOURL OF IMMUNOLOGYENHANCED CELL-MEDIATED PROTECTION AGAINST FATAL ESCHERICHIA1989
• AMERICAN JOURL OF MEDICINEA NEW LOOK AT THE SHARED EPITOPE HYPOTHESIS1988
• TRANSPLANTATIONUSE OF ANTI-L3T4 AND ANTI-IA TREATMENTS FOR PROLONGATION OF XENOGENEIC ISLET TRANSPLANTS1988
• SCIENCEIMMUNOTHERAPY OF THE NONOBESE DIABETIC MOUSE - TREATMENT WITH AN ANTIBODY TO T-HELPER LYMPHOCYTES1988
• JOURL OF CLINICAL INVESTIGATIONADMINISTRATION INVIVO OF RECOMBINT INTERLEUKIN-2 PROTECTS MICE AGAINST SEPTIC DEATH1987
• JOURL OF IMMUNOLOGYMODULATION OF CD4 BY ANTIGENIC ACTIVATION1987
• METHODS IN ENZYMOLOGYCLONING OF HUMAN ALLOREACTIVE T-CELLS1987
• JOURL OF EXPERIMENTAL MEDICINELONG-TERM HUMORAL UNRESPONSIVENESS INVIVO, INDUCED BY TREATMENT WITH MONOCLOL-ANTIBODY AGAINST L3T41986
• ANLS OF THE NEW YORK ACADEMY OF SCIENCESGENE CONVERSION - A MECHANISM TO EXPLAIN HLA-D REGION AND DISEASE ASSOCIATION1986
• JOURL OF CLINICAL INVESTIGATIONSHARED T-CELL RECOGNITION SITES ON HUMAN HISTOCOMPATIBILITY LEUKOCYTE ANTIGEN CLASS1986
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMHUMAN T-CELL CLONES USED TO DEFINE FUNCTIOL EPITOPES ON HLA CLASS-II MOLECULES1986
• IMMUNOLOGICAL INVESTIGATIONSHUMAN T-CELL CLONES AS DIAGNOSTIC-TOOLS AND POTENTIAL THERAPEUTIC REAGENTS0

Dr. C. garrison Fathman MD's Practice location