Dr. Bruce S Klein MD
Infectious Disease Specialist (Pediatric) | Pediatric Infectious Diseases
2880 University Ave Madison WI, 53705About
Dr. Klein is a Professor in the Department of Pediatrics, Internal Medicine, and Medical Microbiology and Immunology, at the University of Wisconsin School of Medicine and Public Health. He maintains ...
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Using new genetic tools to study the pathogenesis of Blastomyces dermatitidis.
- Linking fungal morphogenesis with virulence.
- Cluster of pulmonary blastomycosis in a rural community: evidence for multiple high-risk environmental foci following a sustained period of diminished precipitation.
- BAD1, an essential virulence factor of Blastomyces dermatitidis, suppresses host
- Requisite elements in vaccine immunity to Blastomyces dermatitidis: plasticity uncovers vaccine potential in immune-deficient hosts.
- Agrobacterium tumefaciens integrates transfer DNA into single chromosomal sites of dimorphic fungi and yields homokaryotic progeny from multinucleate yeast.
- Vaccine immunity to pathogenic fungi overcomes the requirement for CD4 help in exogenous antigen presentation to CD8+ T cells: implications for vaccine development in immune-deficient hosts.
- Sequence elements necessary for transcriptional activation of BAD1 in the yeast
- Exploiting type 3 complement receptor for TNF-alpha suppression, immune evasion, and progressive pulmonary fungal infection.
- Progress in vaccination for histoplasmosis and blastomycosis: coping with cellular immunity.
- IL-12 is required for induction but not maintenance of protective, memory responses to Blastomyces dermatitidis: implications for vaccine development in immune-deficient hosts.
- CD28 is required for optimal induction, but not maintenance, of vaccine-induced immunity to Blastomyces dermatitidis.
- Calcium binding by the essential virulence factor BAD-1 of Blastomyces dermatitidis.
- Differential requirements of T cell subsets for CD40 costimulation in immunity to Blastomyces dermatitidis.
- Global control of dimorphism and virulence in fungi.
Awards
- 2011, 2011 Best Doctors in America
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