Dr. Mark R Mariani M.D.
Physiatrist (Physical Medicine) | Sports Medicine
3124 S 19th St Tacoma WA, 98405About
Dr. Mark Mariani is a physiatrist practicing in Tacoma, WA. Dr. Mariani is a medical doctor specializing in physical medicine and rehabilitation. As a physiatrist, Dr. Mariani focuses on a patients ability to function, and can treat multiple conditions that affect the brain, nerves, spine, bones, muscles, joints, ligaments and tendons. Dr. Mariani can diagnose and treat pain that is a result of injury, disease or a disabling condition. Physiatrists often lead a team of physical therapists, occupational therapists and physicians in a patients treatment or prevention plan.
Board Certification
Family MedicineAmerican Board of Family MedicineABFM- Sports Medicine
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Dihydrotestosterone as a selective cellular/nuclear localization vector for anti-gene peptide nucleic acid in prostatic carcinoma cells.
- Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats.
- Effects of N-methyl-N-nitrosourea on transcriptionally active and inactive nucleosomes: macromolecular damage and DNA repair.
- Factors affecting nucleosome structure in transcriptionally active chromatin. Histone acetylation, nascent RNA and inhibitors of RNA synthesis.
- Inhibition of Burkitt's lymphoma cells growth in SCID mice by a PNA specific for a regulatory sequence of the translocated c-myc.
- Lack of mutagenicity and clastogenicity of PNAEmu-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma.
- PNAEmu can significantly reduce Burkitt's lymphoma tumor burden in a SCID mice model: cells dissemination similar to the human disease.
- Target tissue DNA damage in inbred mouse strains with different susceptibility to the colon carcinogen 1,2-dimethylhydrazine.
- Specific targets of alkylating agents in nuclear proteins of cultured hepatocytes.
- Recovery of transcriptionally active chromatin restriction fragments by binding to organomercurial-agarose magnetic beads. A rapid and sensitive method for monitoring changes in higher order chromatin structure during gene activation and repression.
- Contrasting effects of PNA invasion of the chimeric DMMYC gene on transcription of its myc and PVT domains.
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