Dr. Dwain Louis Thiele MD
Hepatologist | Hepatology
5323 Harry Hines Blvd Dallas TX, 75390About
Dr. Thiele joined the Department of Internal Medicine in 1983, and the Graduate Program in Immunology in the Graduate School of Biomedical Sciences in 1986. He served as Chief of Hepatology from 1998- ...
Provider Details
Expert Publications
Data provided by the National Library of Medicine- T-cell activation and differentiation are regulated by TNF during murine DBA/2-->B6D2F1 intestinal graft-versus-host disease.
- Enhancement of MHC class I-stimulated alloresponses by TNF/TNF receptor (TNFR)1 interactions and of MHC class II-stimulated alloresponses by TNF/TNFR2 interactions.
- Mechanisms of autoimmune liver disease.
- Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms.
- TNF-TNFR2 interactions are critical for the development of intestinal graft-versus-host disease in MHC class II-disparate (C57BL/6J-->C57BL/6J x bm12)F1 mice.
- Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo.
- TNF enhances CD4+ T cell alloproliferation, IFN-gamma responses, and intestinal graft-versus-host disease by IL-12-independent mechanisms.
- The role of TNF-TNFR2 interactions in generation of CTL responses and clearance of hepatic adenovirus infection.
- Ethnic differences in the prevalence of cryptogenic cirrhosis.
- Antiviral cytokines induce hepatic expression of the granzyme B inhibitors, proteinase inhibitor 9 and serine proteinase inhibitor 6.
- Fas and TNFR1, but not cytolytic granule-dependent mechanisms, mediate clearance of murine liver adenoviral infection.
- A calibration comparison of mammographic kVp meters.
- Purification and characterization of dipeptidyl peptidase I from human spleen.
- Autoimmune hepatitis.
- Is anti-TNF therapy safe in patients with rheumatic disease who also have concurrent B or C chronic hepatitis?
Awards
- American Association of Physicians 2004
- Teacher of the Year, UT Southwestern Gastroenterology Training Progra 1994
- American Society for Clinical Investigation 1997
- Best Doctors in America 1996
Professional Memberships
- Member American Association for Immunologists
- Member American Association for the Study of Liver Diseases
- Member American Gastroenterological Association
Fellowships
- University of Texas Southwestern Medical School, Gastroenterology & Liver Diseases 1983
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