Dr. James Elliott Bradner MD
Hematologist-Oncologist | Hematology & Oncology
44 Binney St Dana-Farber Cancer I Boston MA, 02115About
Dr. Bradner received his MD from The University of Chicago in 1999. He completed his postgraduate training in Internal Medicine at Brigham and Women's Hospital, followed by a fellowship in Medical Onc ...
Education and Training
Univ of Chicago, Pritzker Sch of Med, Chicago Il 1999
Pritzker School Of Med University Of Chicago 1999
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Hematology
Internal MedicineAmerican Board of Internal MedicineABIM- 2002
Internal MedicineAmerican Board of Internal MedicineABIM- Medical Oncology- 2005
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma.
- Small-molecule inhibition of proteasome and aggresome function induces
- Intracellular protein degradation and its therapeutic implications.
- A robust small-molecule microarray platform for screening cell lysates.
- Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity.
- A method for the covalent capture and screening of diverse small molecules in a microarray format.
- Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.
- Structural origin of selectivity in class II-selective histone deacetylase inhibitors.
- HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.
- Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.
- Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole.
- A pulse at the heart of targeted therapy.
- Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold.
- Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.
- Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
Awards
- 2010-2011 Damon Runyon-Rachleff Innovation Award
- 2010 Smith Family Award for Excellence in Biomedical Research
- Dunkin Donuts 2007 Rising Star Award
- American Society of Hematology 2006 Fellow Scholar Award
- Brigham & Women's Hospital 2005 Distinguished Excellence in Teaching Award
- Harvard Medical School 2002 Golden Hammer Teaching Award
- 1995 Bok Teaching Award
- 2011 Smith Family Foundation Award for Biomedical Research Excellence
- 2013 Alpha Omega Alpha Beta Chapter, Univ. of Chicago Alumni Honoree
- 2007-2008 Dunkin Donuts Rising Star Award
Treatments
- Multiple Myeloma, Stem Cell Transplant
Fellowships
- Dana-Farber/Partners CancerCare, Hematology/Oncology 2002
- Dana Farber Cancer Institute, Fellow 2002
- Dana Farber Cancer Institute, Fellow:Hematology/Oncology 2002
- Broad Institute of Harvard and MIT, Fellow:Chemical Pathology 2004
Dr. James Elliott Bradner MD's Practice location
Practice At 44 Binney St Dana-Farber Cancer Institute
44 Binney St Dana-Farber Cancer I -Boston, MA 02115Get Direction
Dr. James Elliott Bradner MD's reviews
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Stem Cell Therapy Puts 4-year-old's Ultra Rare Lymphoma in Remission4-year-old Jovon Moss was diagnosed with X-linked Lymphoproliferative Syndrome, a rare disorder of the immune system that led him to being taken back and forth to the hospital since his 3rd birthday.Jovon’s journey began in September of last year, when his mother, Brittany Fluellen, first began to...
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Roles of the National Coalition for Cancer SurvivorshipThe National Coalition for Cancer Survivorship (NCCS) is a nonprofit, cancer advocacy organization that is located just outside of Washington D.C. To date, it is the oldest survivor-led cancer advocacy organization in the United States.The NCCS represents millions of Americans who share a common...
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- Multiple Myeloma: What is Autotransplantation?
During a stem cell transplantation or autotransplantation, the patient receives high chemotherapy dosage which is sometimes done to the entire body to get rid of the cells that are in the bone marrow (including the myeloma cells). Afterwards, the patient receives new stem cells to form...
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A team led by a consultant haematology specialist takes care of you if you are a multiple myeloma patient. The team discusses your situation and suggests the best treatment for you, but you will finally decide.It may be paramount to compile a list of questions which you will ask the specialist...
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Touchdown For Lymphoma: Two Teams Put Rivalry Aside For a CauseEveryone knows that some rivalries can get pretty heated - especially when sports are involved. However, two football teams recognize that there is something more important - supporting a girl with Hodgkin's lymphoma. Although she was a cheerleader for the football team, they are now turning the...
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Nearest Hospitals
BRIGHAM AND WOMEN'S HOSPITALl
75 FRANCIS STREET BOSTON MA 2115BOSTON CHILDREN'S HOSPITALl
300 LONGWOOD AVENUE BOSTON MA 2115