Dr. Dean D. Metcalfe M.D.
Rheumatologist | Rheumatology
Nih 10 Center Dr 10/11c207 Bethesda MD, 20892About
Dr. Dean Metcalfe is a rheumatologist practicing in Bethesda, MD. Dr. Metcalfe specializes in the treatment of musculoskeletal diseases and systematic autoimmune conditions that can affect the bones, muscles or bones. Eventually, if not treated, these illnesses can also impact the skin, eyes, nervous system and internal organs. Dr. Metcalfe treats diseases similar to orthopedists but does not perform surgery. Often times, research is conducted to find potential alternatives for the patients illness.
Board Certification
Allergy and ImmunologyAmerican Board of Allergy and ImmunologyABAI
Internal MedicineAmerican Board of Internal MedicineABIM- Rheumatology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Mast cells express connexins on their cytoplasmic membrane.
- Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB.
- Murine mast cells exposed to mercuric chloride release granule-associated N-acetyl-beta-D-hexosaminidase and secrete IL-4 and TNF-alpha.
- Eotaxin potentiates antigen-dependent basophil IL-4 production.
- Receptor-mediated modulation of murine mast cell function by alpha-melanocyte stimulating hormone.
- Mast cell-T cell interactions.
- Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13).
- Frequency and characterization of antigen-specific IL-4- and IL-13- producing basophils and T cells in peripheral blood of healthy and asthmatic subjects.
- Demonstration that platelet-activating factor is capable of activating mast cells and inducing a chemotactic response.
- Human mast cells express the hyaluronic-acid-binding isoform of CD44 and adhere to hyaluronic acid.
- Analysis of the surface expression of c-kit and occurrence of the c-kit Asp816Val
- Mastocytosis complicating pregnancy.
- Mast cells in innate immunity.
- Differential diagnosis of the patient with unexplained flushing/anaphylaxis.
- Expression of a functional high-affinity IgG receptor, Fc gamma RI, on human mast cells: Up-regulation by IFN-gamma.
Dr. Dean D. Metcalfe M.D.'s Practice location
Dean Metcalfe
Nih 10 Center Dr 10/11c207 -Bethesda, MD 20892Get Direction
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Nearest Hospitals
SUBURBAN HOSPITALl
8600 OLD GEORGETOWN ROAD BETHESDA MD 20814HOLY CROSS HOSPITALl
1500 FOREST GLEN ROAD SILVER SPRING MD 20910SIBLEY MEMORIAL HOSPITALl
5255 LOUGHBORO RD NW WASHINGTON DC 20016