Dr. David Nachum Cornfield M.D.
Pulmonologist (Pediatric) | Pediatric Pulmonology
770 Welch Rd Suite 350 Palo Alto CA, 94304About
My father was a physician, I spent a lot of time by his side, going on house calls and visiting the hospital with him. The good he brought into the world and the healing power he possessed left a trem ...
Board Certification
PediatricsAmerican Board of PediatricsABP- Pediatric Critical Care Medicine
PediatricsAmerican Board of PediatricsABP- Pediatric Pulmonology- 1994
Provider Details
Expert Publications
Data provided by the National Library of Medicine- NO causes perinatal pulmonary vasodilation through K+-channel activation and intracellular Ca2+ release.
- Inhaled nitric oxide in premature neonates with severe hypoxaemic respiratory failure: a randomised controlled trial.
- Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs.
- Fetal rabbit pulmonary artery smooth muscle cell response to ryanodine is developmentally regulated.
- Chronic intrauterine pulmonary hypertension decreases calcium-sensitive potassium channel mRNA expression.
- Pulmonary vascular response to normoxia and K(Ca) channel activity is developmentally regulated.
- Ca(2+)-activated K(+) channels modulate basal and E(2)beta-induced rises in uterine blood flow in ovine pregnancy.
- Polycyclic aromatic hydrocarbon diol epoxides increase cytosolic Ca(2+) of airway epithelial cells.
- Oxygen-induced fetal pulmonary vasodilation is mediated by intracellular calcium activation of K(Ca) channels.
- Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model.
- Pulmonary vascular K+ channel expression and vasoreactivity in a model of congenital heart disease.
- Chronic intrauterine pulmonary hypertension compromises fetal pulmonary artery smooth muscle cell O2 sensing.
- A rose by any other name is yet a rose: acute respiratory failure in children.
- Natural history of pulmonary complications in children after bone marrow transplantation.
- Oxygen increases ductus arteriosus smooth muscle cytosolic calcium via release of calcium from inositol triphosphate-sensitive stores.
Awards
- President, Society for Pediatric Research 2009-2010
- Pediatric Academic Societies-Steering Committee, PAS 2010-2014
- Study Section Member-RIBT, NIH 2009-2014
- Editorial Board Member, American Journal of Physiology-Lung, Cell and 2008-2014
- Editorial Board Member, Pediatrics 2010-2014
- Anne T. and Robert M. Bass Professor of Pulmonary Medicine, Stanford 2006-2014
Fellowships
- Children's Hospital-Denver, Aurora, CO 1993
- Children's Hospital-Denver CO 1993
Publications
- PediatricsUse of Electronic Medical Record-Enhanced Checklist and Electronic Dashboard to Decrease CLABSIs.2014
- Current opinion in pediatricsAcute respiratory distress syndrome in children: physiology and magement.2013
- Pediatric critical care medicineEmbedding time-limited laboratory orders within computerized provider order entry reduces2013
- JAMA : the jourl of the American Medical AssociationCreation and retention of the next generation of physician-scientists for child health research.2013
- Circulation researchHypoxia-inducible factor2013
- AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYVoltage-Dependent Anion Channel2012
- SCIENCE TRANSLATIOL MEDICINEQuantitative Alysis of the Human Airway Microbial Ecology Reveals a Perv2012
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYInhibiting NF-kappa B in the developing lung disrupts angiogenesis and alveolarization2012
- ACTA PAEDIATRICADecisions about life-sustaining measures in children: in whose best interests?2012
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYHypoxia-inducible factor2012
- PEDIATRIC RESEARCHSociety for Pediatric Research 2010 Presidential Address2011
- PEDIATRICSComputerized Physician Order Entry With Decision Support Decreases Blood Transfusions in Children2011
- PEDIATRIC CRITICAL CARE MEDICINEThe Accreditation Council for Graduate Medical Education proposed work hour regulations2011
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYRho kise modulates posttal adaptation of the pulmory circulation through separate effects on2010
- Cornfield, D. N.Developmental Regulation of Oxygen Sensing and Ion Channels in the Pulmory Vasculature2010
- JOURL OF NEUROSURGERY-PEDIATRICSSuccessful treatment of severe cerebral vasospasm following hemorrhage of an arteriovenous mal2009
- PEDIATRIC CRITICAL CARE MEDICINEUtility of blood cultures in postoperative pediatric intensive care unit patients2009
- CHESTQuantitative Alysis of Longitudil Response to Aerosolized Granulocyte-Macrophage Colony2009
- PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMDevelopmental regulation of hypoxia-inducible factor 12007
- BLOODThe unexpected effect of cyclosporin A on CD56(+)CD16(-)2007
- ANESTHESIA AND ALGESIACase-series of nurse-administered nitrous oxide for uriry catheterization in children2007
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYChronic intrauterine pulmory hypertension increases capacitative calcium entry2007
- PEDIATRIC RESEARCHWnt5a is required for cardiac outflow tract septation in mice2007
- GENE EXPRESSION PATTERNSLung specific developmental expression of the Xenopus laevis surfactant protein C and B genes2007
- PEDIATRIC RESEARCHAcute normoxia increases fetal pulmory artery endothelial ceff cytosolic Ca2+ via Ca2+2006
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYOxygen tension modulates the expression of pulmory vascular BKCa channel alpha- and beta-subunits2006
- BIOLOGY OF BLOOD AND MARROW TRANSPLANTATIONInflammatory cytokines2006
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYChronic intrauterine pulmory hypertension selectively modifies pulmory artery smooth muscle cell2006
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYOxygen increases ductus arteriosus smooth muscle cytosolic calcium via release of calcium from2005
- Pediatric critical care medicineExtubation failure in pediatric intensive care incidence and outcomes.2005
- BIOLOGY OF BLOOD AND MARROW TRANSPLANTATIONtural history of pulmory complications in children after bone marrow transplantation2005
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYMyeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation2004
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYChronic intrauterine pulmory hypertension compromises fetal pulmory artery smooth muscle cell O2003
- AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINEA rose by any other me is yet a rose - Acute respiratory failure in children2003
- JOURL OF HEART AND LUNG TRANSPLANTATIONSafety of inhaled nitric oxide after lung transplantation2003
- PEDIATRICSContinuous propofol infusion in 142 critically ill children2002
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYPulmory vascular K+ channel expression and vasoreactivity in a model of congenital heart disease2002
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYContribution of the K-Ca channel to membrane potential2002
- CRITICAL CARE MEDICINEInteractive effects of high-frequency oscillatory ventilation2002
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYOxygen-induced fetal pulmory vasodilation is mediated by intracellular calcium activation of K2001
- AMERICAN JOURL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGYA beta-peptides enhance vasoconstriction in cerebral circulation2001
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYEffects of oxidant stress on inflammation2001
- AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYPolycyclic aromatic hydrocarbon diol epoxides increase cytosolic Ca2+ of airway epithelial cells2001
- AMERICAN JOURL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGYCa2+-activated K+ channels modulate basal2001
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYPulmory vascular response to normoxia and K-Ca channel activity is developmentally regulated2001
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYChronic intrauterine pulmory hypertension decreases calcium2000
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYFetal rabbit pulmory artery smooth muscle cell response to ryanodine is developmentally regulated2000
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYVoltage-gated K+-channel activity in ovine pulmory vasculature is developmentally regulated2000
- Cornfield, D. N., Mayrd, R. C., deRegnier, R. A., Guiang, S. F., BarbaRandomized, controlled trial of low-dose inhaled nitric oxide in the treatment of term and near1999
- JOURL OF LABORATORY AND CLINICAL MEDICINEAerosol delivery of diethylenetriamine1999
- LANCETInhaled nitric oxide in premature neotes with severe hypoxaemic respiratory failure1999
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYInteractions of keratinocyte growth factor with a nitrating species after marrow transplantation1999
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYNO causes perital pulmory vasodilation through K+-channel activation and intracellular Ca2+ release1999
- JOURL OF PEDIATRICSMulticenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas1999
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYK+-channel blockade inhibits shear stress-induced pulmory vasodilation in the ovine fetus1999
- CIRCULATIONEffects of inhaled nitric oxide and oxygen in high-altitude pulmory edema1998
- AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYA maturatiol shift in pulmory K+ channels, from Ca2+ sensitive to voltage dependent1998
- Weir, E. K., Reeve, H. L., Cornfield, D. N., TRISTANIFIROUZI, M., PeteDiversity of response in vascular smooth muscle cells to changes in oxygen tension1997
- AMERICAN JOURL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGYVentilation-induced pulmory vasodilation at birth is modulated by potassium channel activity1996
- PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMOxygen causes fetal pulmory vasodilation through activation of a calcium1996
- JOURL OF LABORATORY AND CLINICAL MEDICINEInhalatiol nitric oxide in pulmory parenchymal and vascular disease1996
- EUROPEAN RESPIRATORY JOURLHYPOXIA POTENTIATES NITRIC1995
- PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMCA2+-INHIBITABLE ADENYLYL1995
- CELL CALCIUMREDUCED PO2 ALTERS THE BEHAVIOR OF FURA-2 AND INDO-1 IN BOVINE PULMORY-ARTERY ENDOTHELIAL-CELLS1994
- AMERICAN JOURL OF PHYSIOLOGYACUTE REDUCTIONS IN PO-2 DEPOLARIZE PULMORY-ARTERY ENDOTHELIAL-CELLS AND DECREASE [CA2+](I)1994
- AMERICAN JOURL OF PHYSIOLOGYACUTE-HYPOXIA CAUSES MEMBRANE DEPOLARIZATION AND CALCIUM INFLUX IN FETAL PULMORY1994
- AMERICAN JOURL OF PHYSIOLOGYACUTE-HYPOXIA INCREASES CYTOSOLIC CALCIUM IN FETAL PULMORY-ARTERY SMOOTH-MUSCLE CELLS1993
- AMERICAN JOURL OF PHYSIOLOGYEFFECTS OF OXYGEN AND EXOGENOUS L-ARGININE ON EDRF ACTIVITY IN FETAL PULMORY CIRCULATION1993
- AMERICAN JOURL OF PHYSIOLOGYROLE OF ATP-SENSITIVE POTASSIUM CHANNELS IN OVINE FETAL PULMORY VASCULAR TONE1992
- AMERICAN JOURL OF PHYSIOLOGYEFFECTS OF BIRTH-RELATED STIMULI ON L-ARGININE-DEPENDENT PULMORY VASODILATION IN OVINE FETUS1992
Experience & Accolades
- Interim Chair 2003 - 2004 Department of Pediatrics University of Minnesota
- Director 2006 - 2014 Center for Excellence in Pulmonary Biology, Stanford
- Division Director 2007 - 2014 Pediatric Critical Care Medicine, Stanford
- Division Director 2006 - 2014 Pulmonary Medicine, Stanford
- Fellowship Director_Pediatric Critical Care Medicine2007 - 2014 Stanford
- Medical Director_Respiratory Therapy2010 - 2014 Lucile Packard Children's Hospital
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