Dr. Calvin Mackay is a pediatric orthopaedic surgeon practicing in Provo, UT. Dr. Mackay specializes in the diagnosis, treatment and rehabilitation of injuries, diseases and disorders of the bodys musculoskeletal system in children. As a pediatric orthopaedic surgeon, Dr. Mackay tends to childrens bones, ligaments, muscles, joints, nerves and tendons. Pediatric orthopaedic surgeons can treat newborns to teenagers. Some conditions Dr. Mackay treats include gait abnormalities like limping, limp and spine deformities, broken bones and bone and joint infections.
- HIV-1 infectability of CD4+ lymphocytes with relation to beta-chemokines and the CCR5 coreceptor.
- Ethical considerations in research on Huntington's disease.
- Dual personality of memory T cells.
- Monoclonal antibody screening of a phage-displayed random peptide library reveals mimotopes of chemokine receptor CCR5: implications for the tertiary structure of the receptor and for an N-terminal binding site for HIV-1 gp120.
- The role of chemokine receptors in primary, effector, and memory immune responses.
- Enhanced levels of functional HIV-1 co-receptors on human mucosal T cells demonstrated using intestinal biopsy tissue.
- T-cell function and migration. Two sides of the same coin.
- Follicular homing T helper (Th) cells and the Th1/Th2 paradigm.
- Chemokines: immunology's high impact factors.
- Immunology. Memory T cells--local heroes in the struggle for immunity.
- T cell effector subsets: extending the Th1/Th2 paradigm.
- Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells.
- The question of method in ethics consultation: the IRB frontier.
- Levels of BAFF in serum in primary biliary cirrhosis and autoimmune diabetes.
- Carcinoma of vulva following granuloma inguinale.
- The significance of local vascular changes in bleeding peptic ulcer.
- Osteomyelitis of the Os calcis following triple arthrodesis.
- Tissue-specific migration pathways by phenotypically distinct subpopulations of memory T cells.
- Altered patterns of T cell migration through lymph nodes and skin following antigen challenge.
- Failure of antihistamine therapy in severe sulfadiazine hypersensitivity.
- Migration pathways and immunologic memory among T lymphocytes.
- Overlapping gene expression profiles in rheumatoid fibroblast-like synoviocytes induced by the proinflammatory cytokines interleukin-1 beta and tumor necrosis factor.
- Lymphocyte homing. Skin-seeking memory T cells.
- Epitopes of the T19 lymphocyte surface antigen are extensively conserved in ruminants.
- Expression of the "T19" and "null cell" markers on gamma delta T cells of the sheep.
- Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration.
- Prominence of gamma delta T cells in the ruminant immune system.
- T-cell memory: the connection between function, phenotype and migration pathways.
- Marked variations in gamma delta T cell numbers and distribution throughout the life of sheep.
- Polymorphism in the 5' regulatory region of the B-lymphocyte activating factor gene is associated with the Ro/La autoantibody response and serum BAFF levels in primary Sjogren's syndrome.
- Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches.
- Informed consent for biomedical research in acute care medicine.
- Other surface antigens identified on sheep leukocytes.
- Summary of workshop findings for leukocyte antigens of sheep.
- Analysis of gamma delta T cells in ruminants reveals further heterogeneity in gamma delta T-cell features and function among species.
- Naive and memory T cells show distinct pathways of lymphocyte recirculation.
- Sheep lymphocyte antigens (OLA). I. Major histocompatibility complex class I molecules.
- Thymocyte subpopulations during early fetal development in sheep.
- A monoclonal antibody to the p220 component of sheep LCA identifies B cells and a unique lymphocyte subset.
- Unusual expression of CD2 in sheep: implications for T cell interactions.
- Gamma/delta T cells express a unique surface molecule appearing late during thymic development.
- A large proportion of bovine T cells express the gamma delta T cell receptor and show a distinct tissue distribution and surface phenotype.
- Surface expression of differentiation antigens on lymphocytes in the ileal and jejunal Peyer's patches of lambs.
- Immunology and veterinary science.
- Three distinct subpopulations of sheep T lymphocytes.
- The sheep analogue of leucocyte common antigen (LCA).
- Lymphocyte subsets show marked differences in their distribution between blood and the afferent and efferent lymph of peripheral lymph nodes.
- Ontogeny of ovine lymphocytes. II. An immunohistological study on the development of T lymphocytes in the sheep fetal spleen.
- Ontogeny of ovine lymphocytes. III. An immunohistological study on the development of T lymphocytes in sheep fetal lymph nodes.
- Ontogeny of ovine lymphocytes. I. An immunohistological study on the development of T lymphocytes in the sheep embryo and fetal thymus.
- Lymphocyte antigens of sheep: identification and characterization using a panel of monoclonal antibodies.
- Four antigens expressed on most ovine cell types.
- Characterization of two sheep lymphocyte differentiation antigens, SBU-T1 and SBU-T6.
- Surface antigens, SBU-T4 and SBU-T8, of sheep T lymphocyte subsets defined by monoclonal antibodies.
- Sheep lymphocyte antigens (OLA). II. Major histocompatibility complex class II molecules.
- Expression and modulation of CD44 variant isoforms in humans.
- Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated.
- Case: responding to a request for genetic testing that is still in the lab.
- Lymphocyte recirculation and life span in vivo.
- Homing of naive, memory and effector lymphocytes.
- Cell adhesion in the immune system.
- Immunological memory.
- Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential.
- Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.
- The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates.
- Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.
- Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2.
- Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells.
- Characterisation of leucocytic somatic cells in bovine milk.
- Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin alpha 4 beta 7.
- Phenotype, and migration properties of three major subsets of tissue homing T cells in sheep.
- Discrete steps in binding and signaling of interleukin-8 with its receptor.
- Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.
- CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia.
- The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes.
- HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5.
- Chemokine receptors and T cell chemotaxis.
- CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro.
- Chemokines: what chemokine is that?
- Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue.
- High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.
- Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells.
- Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding.
- Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection.
- Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines.
- The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions.
- Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils.
- Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes.
- Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia.
- The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig.
- The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow.
- Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of beta-chemokines.
- Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation.
- Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses.
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