Dr. Clayton A Wiley MD,PHD is a top Doctor in Pittsburgh, PA.With a passion for the field and an unwavering commitment to their specialty, Dr. Clayton A Wiley MD,PHD is an expert in changing the lives of their patients for the better.Through their designated cause and expertise in the field, Dr. Clayton A Wiley MD,PHD is a prime example of a true leader in health care.As a leader and expert in their field, Dr. Clayton A Wiley MD,PHD is passionate about enhancing patient quality of life. They embody the values of communication, safety, and trust when dealing directly with patients.In Pittsburgh, PA, Dr. Clayton A Wiley MD,PHD is a true asset to their field and dedicated to the profession of medicine.
Education and Training
Univ of Ca, San Diego, Sch of Med, La Jolla Ca 1981
PathologyAmerican Board of PathologyABP- Neuropathology
- Macrophages relate presynaptic and postsynaptic damage in simian immunodeficiency virus encephalitis.
- Cell cycle proteins exhibit altered expression patterns in lentiviral-associated encephalitis.
- Recovery of replication-competent HIV type 1-infected circulating monocytes from individuals receiving antiretroviral therapy.
- A reliable primary human CNS culture protocol for morphological studies of dendritic and synaptic elements.
- Detection of HIV-1 DNA in microglia/macrophages, astrocytes and neurons isolated from brain tissue with HIV-1 encephalitis by laser capture microdissection.
- February 2003: a 53-year-old male with new onset seizures.
- Fatal fulminant pan-meningo-polioencephalitis due to West Nile virus.
- Human immunodeficiency virus infection of the brain: pitfalls in evaluating infected/affected cell populations.
- PET imaging of brain macrophages using the peripheral benzodiazepine receptor in a macaque model of neuroAIDS.
- October 2003: a 59-year-old woman with sudden onset of diplopia. Listerial
- HIV-1/AIDS neuropathology in a Canadian teaching centre.
- Destruction of extracellular matrix proteoglycans is pervasive in simian retroviral neuroinfection.
- Neuronal intranuclear inclusion disease without polyglutamine inclusions in a child.
- Pocket proteins p107 and p130 exhibit increased expression in macrophages during SIV encephalitis.
- Longitudinal analysis of monocyte/macrophage infection in simian immunodeficiency virus-infected, CD8+ T-cell-depleted macaques that develop lentiviral encephalitis.
- Longitudinal analysis of activation markers on monocyte subsets during the development of simian immunodeficiency virus encephalitis.
- The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging.
- A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation.
- Systemic distribution of West Nile virus infection: postmortem immunohistochemical study of six cases.
- The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging.
- Telepathology for intraoperative neuropathologic consultations at an academic medical center: a 5-year report.
- Activated macrophages in HIV encephalitis and a macaque model show increased [3H](R)-PK11195 binding in a PI3-kinase-dependent manner.
- The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds to activated and infected brain macrophages in areas of synaptic degeneration: implications for PET imaging of neuroinflammation in lentiviral encephalitis.
- PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET.
- Systemic and brain macrophage infections in relation to the development of simian immunodeficiency virus encephalitis.
- Longitudinal in vivo positron emission tomography imaging of infected and activated brain macrophages in a macaque model of human immunodeficiency virus encephalitis correlates with central and peripheral markers of encephalitis and areas of synaptic
- YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor.
- Brain extracellular matrix in neurodegeneration.
- The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders.
- Imaging microglial activation during neuroinflammation and Alzheimer's disease.
- Comparison of telepathology systems in neuropathological intraoperative consultations.
- Key role of T cell defects in age-related vulnerability to West Nile virus.
- Are MD-PhD programs meeting their goals? An analysis of career choices made by graduates of 24 MD-PhD programs.
- YKL-40 is directly produced by tumor cells and is inversely linked to EGFR in glioblastomas.
- Modeling host responses in ferrets during A/California/07/2009 influenza infection.
- In vivo CHI3L1 (YKL-40) expression in astrocytes in acute and chronic
- GM-CSF increases mucosal and systemic immunogenicity of an H1N1 influenza DNA
- Medical Scientist Training Programs: a modest proposal to eliminate federal funding in favor of individual fellowships.
- Microglia: key innate immune cells of the brain.
- Immune response to the West Nile virus in aged non-human primates.
- Interinstitutional and interstate teleneuropathology.
- Acute murine H5N1 influenza A encephalitis.
- Astrocyte and macrophage regulation of YKL-40 expression and cellular response in neuroinflammation.
- Absence of fetal transmission of H1N1 despite severe maternal infection.
- Elicitation of anti-1918 influenza virus immunity early in life prevents
- Antibody breadth and protective efficacy are increased by vaccination with computationally optimized hemagglutinin but not with polyvalent hemagglutinin-based H5N1 virus-like particle vaccines.
- A computationally optimized hemagglutinin virus-like particle vaccine elicits broadly reactive antibodies that protect nonhuman primates from H5N1 infection.
- Preventive immunization of aged and juvenile non-human primates to β-amyloid.
- Molecular imaging of microglia/macrophages in the brain.
- Psychostimulant abuse and neuroinflammation: emerging evidence of their interconnection.
- Exacerbation of experimental autoimmune encephalomyelitis in the absence of breast regression protein 39/chitinase 3-like 1.
- The cost of silencing HIV in the brain.
- H1N1, but not H3N2, influenza A virus infection protects ferrets from H5N1 encephalitis.
- Coxsackievirus B4 myocarditis and meningoencephalitis in newborn twins.
- A 67 Year-Old Man with Multiple Sclerosis and New Cerebellar Lesions.
- Human Parechovirus 3 Meningitis and Fatal Leukoencephalopathy.
- Emerging Infections of CNS: Avian Influenza A Virus, Rift Valley Fever Virus and Human Parechovirus.
- Cerebrospinal Fluid Biomarkers of Simian Immunodeficiency Virus Encephalitis : CSF Biomarkers of SIV Encephalitis.
- Delta inulin-derived adjuvants that elicit Th1 phenotype following vaccination reduces respiratory syncytial virus lung titers without a reduction in lung immunopathology.
- Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques.
- The spectrum of neuropathological changes associated with congenital Zika virus infection.
- Human Zika and West Nile virus neurological infections: What is the difference?
- Univ Ca San Diego Med Ctr, Neuropathology; Moffitt Hosp Univ Of Ca, Anatomic And Clinical Pathology
- U Calif San Deigo
Dr. Clayton A Wiley MD,PHD's Practice location
Pittsburgh, PA 15213Get Direction
Dr. Clayton A Wiley MD,PHD's reviewsWrite Review
- Tips for Keeping Great Documentation of Nursing Career
Nursing is not a profession just about skills, it is also about people's vocational needs.Given their role as caregivers, it is obvious that these professionals should be interested in their patients and what they have to say about the way they feel.Some time ago the following question was asked to...
- "Dining With Diabetes" Reaches Penn State With its Online Course
Patients newly-diagnosed with diabetes may have a difficult time adjusting to a new lifestyle of constantly managing the disease and eliminating certain foods from their diet. Especially when they knew nothing about the disease before.The ‘Dining With Diabetes’ program was created for newly...
- Kidney Stones: Is There Something Wrong With My Kidneys?
Kidney Stones: Is There Something Wrong With My Kidneys?When crystal-like structures form in the kidney are referred to as kidney stones. Kidney stones are mostly known to occur in people aged from the age of 30-60 years. Most of these people are men. According to research, around 15% of people in...
- Questions You Should Be Asking Your Doctor
IntroductionAlthough doctors have the best intentions, it does not always mean that they will perfectly recognize their patient’s greatest need. For this reason, patients also need to take an active role when it comes to communicating with their doctor.One of the best ways to make sure that...
- What Is Pyrexia: Causes, Symptoms, and Treatment
Introduction Pyrexia is the medical term for fever, in which the human body temperature rises above the average normal (37 degrees Celsius or 98.6 degrees Fahrenheit). Pyrexia is one of the most common symptoms of numerous medical conditions.There are multiple factors can affect the normal body...
- Anemia Symptoms
What is anemia?Anemia occurs when there are low levels of red blood cells (RBCs) in the body. Red blood cells are the ones that carry oxygen all over the body. So when a person's RBC count is lower than normal, it means that there is not enough oxygen in the blood, causing symptoms of anemia, such...
- Dr. Henkie P Tan MD,PHD3459 5th Ave Pittsburgh PA 15213
- Dr. Jon A Levy MD725 Cherrington Pkwy Coraopolis PA 15108
- Dr. Jeffrey B Mulholland MD725 Cherrington Pkwy Coraopolis PA 15108
- Dr. Jeffrey A Baum MD200 Delafield Rd Pittsburgh PA 15215
- Dr. Steven R Abo MD300 Halket St Pittsburgh PA 15213
- Dr. Oscar C Marroquin MD200 Lothrop St Pittsburgh PA 15213