Dr. Bradley Mark Denker MD
Nephrologist (Kidney Specialist) | Nephrology
133 Brookline Ave Boston MA, 02215About
Dr. Bradley Denker is a nephrologist practicing in Boston, MA. Dr. Denker specializes in the care and treatment of the kidneys. As a nephrologist, Dr. Denker most typically treats conditions like kidney stones, chronic kidney disease, acute renal failure, polycystuc kidney disease, high blood pressure and more. Nephrologists are also experts on kidney transplantation and dialysis. They are usually referred to by primary care physicians for problems related to the kidneys, and while they can perform tests to diagnose kidney disorders, they do not perform surgeries.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Nephrology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Interaction of heterotrimeric G protein Galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor.
- Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin.
- Reassembly of the tight junction after oxidative stress depends on tyrosine kinase activity.
- Expanding role of G proteins in tight junction regulation: Galpha(s) stimulates TJ assembly.
- Association and colocalization of G protein alpha subunits and Purkinje cell protein 2 (Pcp2) in mammalian cerebellum.
- Galpha12 regulates epithelial cell junctions through Src tyrosine kinases.
- Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.
- Mutagenesis of the amino terminus of the alpha subunit of the G protein Go. In vitro characterization of alpha o beta gamma interactions.
- Promotion of the GTP-liganded state of the Go alpha protein by deletion of the C terminus.
- Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formation.
- Purkinje cell protein-2 (Pcp2) stimulates differentiation in PC12 cells by Gbetagamma-mediated activation of Ras and p38 MAPK.
- Characterization of a mastoparan-stimulated nucleotidase from bovine brain.
- Cell-cell interactions in the kidney: inducible expression of mutant G protein alpha-subunits in Madin-Darby canine kidney cells for studies of epithelial cell junction structure and function.
Dr. Bradley Mark Denker MD's Practice location
Practice At 133 Brookline Ave
133 Brookline Ave -Boston, MA 02215Get Direction
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