Dr. Mark Louis Brantly MD
Pulmonologist | Pulmonary Disease
1600 SW Archer Rd Gainesville FL, 32610About
Dr. Mark Brantly practices Pulmonology in Gainesville, FL. A pulmonologist is a physician who possesses specialized knowledge and skill in the diagnosis and treatment of pulmonary conditions and diseases. Dr. Brantly manages patients who need life support and mechanical ventilation, and is specially trained in diseases and conditions of the chest, particularly pneumonia, asthma, tuberculosis, emphysema, and complicated chest infections.
Education and Training
University of Florida College of Medicine 1979
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Role of human neutrophil peptides in lung inflammation associated with alpha1-antitrypsin deficiency.
- Differential metabolic effects of saturated versus polyunsaturated fats in ketogenic diets.
- Z alpha1-antitrypsin polymerizes in the lung and acts as a neutrophil chemoattractant.
- Genetic testing for alpha1-antitrypsin deficiency.
- Antibody response to aerosolized transgenic human alpha1-antitrypsin.
- Cytotoxic concentrations of alpha-defensins in the lungs of individuals with alpha 1-antitrypsin deficiency and moderate to severe lung disease.
- Short-term atorvastatin treatment enhances specific antibody production following tetanus toxoid vaccination in healthy volunteers.
- Genetic testing of minors for alpha1-antitrypsin deficiency.
- Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro.
- Alpha-1-antitrypsin augmentation therapy in deficient individuals enrolled in the Alpha-1 Foundation DNA and Tissue Bank.
- Augmentation therapy in alpha-1 antitrypsin deficiency: advances and controversies.
- Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model.
- Cytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes.
- Safety and pharmacokinetics of 120 mg/kg versus 60 mg/kg weekly intravenous infusions of alpha-1 proteinase inhibitor in alpha-1 antitrypsin deficiency: a multicenter, randomized, double-blind, crossover study (SPARK).
- Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.
Clinical Trials
- Safety Dose Finding Study of ADVM-043 Gene Therapy to Treat Alpha-1 Antitrypsin (A1AT) Deficiency
- Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)
- Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
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