Dr. Laura L Dugan M.D.
Geriatrician | Geriatric Medicine
200 W Arbor Dr San Diego CA, 92103About
Dr. Laura Dugan practices Geriatric Medicine in San Diego, CA. Geriatricians prevent, manage, and develop care plans that address the special health problems of the elderly. Dr. Dugan works as part of a team with other healthcare providers, to address the natural aging that goes on within the body and to manage multiple medical problems and ensure social support.
Education and Training
Oh State Univ Coll of Med, Columbus Oh 1987
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons.
- Astrocyte mitochondria in in vitro models of ischemia.
- A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties.
- Long-term vitamin E deficiency in mice decreases superoxide radical production in brain.
- Reactive oxygen species and aging: evolving questions.
- Mitochondrial uncoupling proteins in the central nervous system.
- A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice.
- Gender differences in free radical homeostasis during aging: shorter-lived female C57BL6 mice have increased oxidative stress.
- Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase.
- Prolonged alpha-tocopherol deficiency decreases oxidative stress and unmasks alpha-tocopherol-dependent regulation of mitochondrial function in the brain.
- SOD activity of carboxyfullerenes predicts their neuroprotective efficacy: a structure-activity study.
- Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia.
- IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase.
- Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures.
- Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice.
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