Dr. Michael D Hogarty M.D.
Hematologist (Pediatric) | Pediatric Hematology-Oncology
34th & Civic Center Blvd Children's Hospital Philadelphia PA, 19104Rating
5/5
About
I'm a pediatric oncologist with both clinical and research responsibilities. On the clinical side, I have developed expertise in the management of patients with neuroblastoma, germ cell tumors, and hi ...
Education and Training
Columbia Univ Coll of Physicians And Surgeons, New York Ny 1990
Columbia University College of Physicians and Surgeons 1990
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Medical Oncology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification.
- Expression of a MYCN-interacting isoform of the tumor suppressor BIN1 is reduced in neuroblastomas with unfavorable biological features.
- Targeting programmed cell death pathways with experimental therapeutics:
- BH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma.
- Mutations in PIK3CA are infrequent in neuroblastoma.
- Cutaneous metastatic chordoma with concomitant tuberous sclerosis.
- Neuroblastoma.
- Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification.
- N-myc augments death and attenuates protective effects of Bcl-2 in trophically stressed neuroblastoma cells.
- ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.
- Influence of neuroblastoma stage on serum-based detection of MYCN amplification.
- Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas.
- Small-molecule BH3 mimetics to antagonize Bcl-2-homolog survival functions in cancer.
- Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study.
- Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists.
Awards
- 2009 St. Baldrick's Foundation Research Award
- The Children's Hospital of Philadelphia 2005 Foerderer-Murray Award
- University Research Foundation Award, 2005 University of Pennsylvania
- 2000 Burroughs Wellcome Fund Career Award in the Biomedical Sciences
- American Society of Clinical Oncology 1999 Career Development Award
Treatments
- Leukemia
- Dermal Aesthetics
- Extra Corporeal Shockwave Therapy
Professional Memberships
- Member Participation in scientific committees
Fellowships
- Pediatric Hematology/Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA
Experience & Accolades
- Member 2009Member, Search Committee for Pediatric Oncology Survivorship Faculty
- Member2008 - 2014 Co-chair, Pediatric Protocol Review Committee, Division of Oncology and Abramson Family Cancer Cent
- Resident2008 - 2014 Physician- Scientist Mentor Committee
Dr. Michael D Hogarty M.D.'s Practice location
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34th & Civic Center Blvd Children's Hospital -Philadelphia, PA 19104Get Direction
Michael Hogarty
3401& Civic Center Blvd Children's Hospital -Philadelphia, PA 19104Get Direction
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