David Sheff, MD, PhD

Expert Publications

• The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions.
• Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes.
• Isolation and characterization of the rat liver actin N-acetylaminopeptidase.
• Amino-terminal processing of actins mutagenized at the Cys-1 residue.
• Rab8 regulates basolateral secretory, but not recycling, traffic at the recycling endosome.
• Unusual metabolism of the yeast actin amino terminus.
• Deciliation is associated with dramatic remodeling of epithelial cell junctions and surface domains.
• Identification of N-acetylmethionine as the product released during the NH2-terminal processing of a pseudo-class I actin.

Media Releases

Get to know Family Physician Dr. David Sheff, who serves patients in West Liberty, Iowa.

Dr. Sheff is a board-certified family physician who is affiliated with Mercy Family Medicine – West Liberty in West Liberty, Iowa. Mercy Family Medicine – West Liberty is a clinic that is a part of Mercy Iowa City – an acute care hospital and regional referral center that draws patients from throughout southeast Iowa. The mission of Mercy is to heal and comfort the sick and work to improve the health of the community in the spirit of Jesus Christ and the Catholic tradition of the Sisters of Mercy.

Dr. Sheff received his medical degree from the University of Iowa – Carver College of Medicine in Iowa City, Iowa in 1984. He then went on to complete his residency at Cedar Rapids Medical Education Foundation in Cedar Rapids, Iowa.

Dr. Sheff is board-certified in family medicine by the American Board of Family Medicine (ABFM). Founded in 1969, the ABFM is a not-for-profit, private organization whose mission is to improve the health of the public through board certification, residency training, research, leadership development, and promoting the development of the specialty of Family Medicine. The ABFM’s primary role is to support family physicians who are committed to achieving excellence in improving the health of their patients, their families, and their communities.

Family medicine, formerly family practice, is a medical specialty devoted to comprehensive health care for people of all ages. Family physicians, like Dr. Sheff, are often the first person whom a patient sees when seeking healthcare services. They examine and treat patients with a wide range of conditions and refer those with serious ailments to a specialist or appropriate facility.

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