Dr. Alain H Rook MD
Dermatologist
3400 Spruce St 2 Rhoads Pavilion Philadelphia PA, 19104About
Dr. Alain Rook is a dermatologist practicing in Philadelphia, PA. Dr. Rook specializes in skin care. Dermatologists evaluate and manage both common and uncommon skin conditions. These conditions include acne, psoriasis, warts, skin infections, atopic dermatitis, herpes simplex and more. Dermatologists are also experts in more complex skin diseases like impetigo, hidradenitis and milaria. Dr. Rook diagnoses skin problems and develops unique treatments plans for each individual patient.
Education and Training
Univ of Mi Med Sch, Ann Arbor Mi 1975
University of Michigan Medical School 1975
Board Certification
DermatologyAmerican Board of DermatologyABD
Internal MedicineAmerican Board of Internal MedicineABIM- Nephrology
Internal MedicineAmerican Board of Internal MedicineABIM- 1979
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Retinoids synergize with interleukin-2 to augment IFN-gamma and interleukin-12 production by human peripheral blood mononuclear cells.
- Depressed IL-12-mediated signal transduction in T cells from patients with Sézary syndrome is associated with the absence of IL-12 receptor beta 2 mRNA and highly reduced levels of STAT4.
- Extracorporeal photochemotherapy does not suppress T- or B-cell responses to novel or recall antigens.
- Chlamydia pneumoniae inhibits apoptosis in human peripheral blood mononuclear cells through induction of IL-10.
- Successful reversal of recalcitrant hepatic allograft rejection by photopheresis.
- Increased interleukin 5 production in eosinophilic Sézary syndrome: regulation by interferon alfa and interleukin 12.
- Dysregulation of lymphocyte interleukin-12 receptor expression in Sézary syndrome.
- Complete molecular remission during biologic response modifier therapy for Sézary syndrome is associated with enhanced helper T type 1 cytokine production and natural killer cell activity.
- Cutaneous squamous-cell carcinoma.
- The role for interleukin-12 therapy of cutaneous T cell lymphoma.
- Identification of clonal T cells in the blood of patients with systemic sclerosis: positive correlation with response to photopheresis.
- Regression of multifocal, skin-restricted, CD30-positive large T-cell lymphoma with interferon alfa and bexarotene therapy.
- Synergistic enhancement of cell-mediated immunity by interleukin-12 plus interleukin-2: basis for therapy of cutaneous T cell lymphoma.
- Denileukin diftitox for the treatment of panniculitic lymphoma.
- New biologic agents for the treatment of cutaneous T-cell lymphoma.
Awards
- 2012 Philadelphia Super Doctors
- 2004 Recognized annually in Philadelphia Magazine 's Top Docs issue from t
- 2008, 2008, 2008, 2008 Recognized by America's Top Doctors2007
- 2007-2014 Recognized by Best Doctors in America2005-2006
Treatments
- Mycosis Fungoides, Photophoresis, Cutaneous Lymphoma And More
- Psoriasis
- Eczema
- Dermatitis
- Contact Dermatitis
- Lymphoma
- Extra Corporeal Shockwave Therapy
Professional Memberships
- Member International Cutaneous Lymphoma Society
- Member American Academy of Dermatology
- Member American Federation for Medical Research
- Board of Directors Society for Investigative Dermatology
- Member Society for Investigative Dermatology
- Member Pennsylvania Academy of Dermatology ,
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