Dr. Ophir David Klein M.D.,PH.D
Pediatrician
513 Parnassus Ave Room S747, Box 0442 San Francisco CA, 94143About
Dr. Ophir Klein is a specialist in pediatric medical genetics who treats children with craniofacial and dental anomalies as well as general genetic disorders at UCSF Benioff Children's Hospital. His r ...
Education and Training
Yale Univ Sch of Med, New Haven Ct 2000
Yale School of Medicine 2000
Board Certification
Medical GeneticsAmerican Board of Medical GeneticsABMG
PediatricsAmerican Board of PediatricsABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Brachydactylic multiple delta phalanges plus syndrome.
- Unraveling the molecular mechanisms that lead to supernumerary teeth in mice and men: current concepts and novel approaches.
- An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors.
- The branching programme of mouse lung development.
- Temporal analysis of ectopic enamel production in incisors from sprouty mutant mice.
- Revitalization of a diastemal tooth primordium in Spry2 null mice results from increased proliferation and decreased apoptosis.
- Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning.
- Clefting in trisomy 9p patients: genotype-phenotype correlation using microarray comparative genomic hybridization.
- Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors.
- Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor.
- PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.
- FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size.
- Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling.
- A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.
- Expression of microRNAs in the stem cell niche of the adult mouse incisor.
Clinical Trials
Treatments
- Learning Disabilities
- Birth Defects
- Cleft Palate
Fellowships
- UCSF Medical Center, Genetics 2007
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UCSF MEDICAL CENTERl
505 PARNASSUS AVE, BOX 0296 SAN FRANCISCO CA 94143ST MARY'S MEDICAL CENTERl
450 STANYAN ST SAN FRANCISCO CA 94117