Dr. Michael R Knowles MD
Pulmonologist | Pulmonary Disease
101 Manning Dr Chapel Hill NC, 27599About
Dr. Michael Knowles practices Pulmonology in Chapel Hill, NC. A pulmonologist is a physician who possesses specialized knowledge and skill in the diagnosis and treatment of pulmonary conditions and diseases. Dr. Knowles manages patients who need life support and mechanical ventilation, and is specially trained in diseases and conditions of the chest, particularly pneumonia, asthma, tuberculosis, emphysema, and complicated chest infections.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- 1974
Internal MedicineAmerican Board of Internal MedicineABIM- Pulmonary Disease- 1980
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Molecular differentiation of Renibacterium salmoninarum isolates from worldwide
- Recent advances in aerosol therapy.
- Effect of aerosolized uridine-5'-triphosphate on airway clearance with cough in patients with primary ciliary dyskinesia.
- Pulmonary epithelial sodium-channel dysfunction and excess airway liquid in pseudohypoaldosteronism.
- Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides.
- Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis.
- Lung disease associated with the IVS8 5T allele of the CFTR gene.
- A modified technique for measurement of nasal transepithelial potential difference in infants.
- Germline mutations in an intermediate chain dynein cause primary ciliary dyskinesia.
- Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
- 'CFTR-opathies': disease phenotypes associated with cystic fibrosis transmembrane regulator gene mutations.
- Mutations in DNAI1 (IC78) cause primary ciliary dyskinesia.
- What is cystic fibrosis?
- Alterations of stress related proteins in genetically altered mice revealed by two-dimensional differential in-gel electrophoresis analysis.
- Increasing concentration of inhaled saline with or without amiloride: effect on mucociliary clearance in normal subjects.
Fellowships
- UNC Chapel Hill Med School, Pulmonary, NC, USA 1980
- University of North Carolina, Chapel Hill, NC, Pulmonary Diseases 1978
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