Dr. B Longley practices Dermatopathology in Madison, WI. Dermatopathology is a medical specialty that focuses on dermatology and pathology, and involves the diagnosis of various diseases of the skin, hair, and nails by looking at cutaneous diseases at a microscopic and molecular level. By revealing the histology of diseases and results from a specific diagnostic interpretation, Dr. Longley is able to analyze the potential causes of skin diseases at a basic level.
- Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region.
- SCF-KIT pathway in human epidermal melanocyte homeostasis.
- Cutaneous cryoanesthesia does not affect histopathology of biopsy specimens.
- What dermatologists need to know about mast cell disease: a dermatopathologist's view.
- Indolinone derivatives inhibit constitutively activated KIT mutants and kill neoplastic mast cells.
- New approaches to therapy for mastocytosis. A case for treatment with kit kinase inhibitors.
- Classes of c-KIT activating mutations: proposed mechanisms of action and implications for disease classification and therapy.
- The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations.
- Generalized bullae in an infant.
- Paracecal hernia: case report and review of the literature.
- Primary cutaneous B-cell lymphoma. Diagnosis, treatment, and prognosis.
- Acral persistent papular mucinosis.
- Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
- Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis.
- Select cancer testes antigens of the MAGE-A, -B, and -C families are expressed in mast cell lines and promote cell viability in vitro and in vivo.
- Thrombotic lymphocytic vasculitic reaction to intravenous immunoglobulin.
- Epigenetic control of MAGE gene expression by the KIT tyrosine kinase.
- MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines.
- The treatment of mercury poisoning with BAL and peritoneal irrigation.
- KIT masters mast cells in kids, too.
- Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.
- Desmoplastic trichoepithelioma, infiltrative/morpheaform BCC, and microcystic
- Identification of novel small molecules that inhibit protein-protein interactions between MAGE and KAP-1.
- Topical application of bleaching phenols; in-vivo studies and mechanism of action relevant to melanoma treatment.
- Serpiginous erythematous plaques on the feet.
- MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression.
- (V600E)Braf::Tyr-CreERT2::K14-Kitl mice do not develop superficial spreading-like melanoma: keratinocyte Kit ligand is insufficient to "translocate" (V600E)Braf-driven melanoma to the epidermis.
- A generalized annular eruption with occasional vesicles.
- Familial urticaria pigmentosa: report of a family and review of the role of KIT mutations.
- A 38-year-old woman with eyelid discoloration. Heliotrope-like manifestation of adult-onset Still disease (AOSD).
- Black spots in the returning traveler.
- Role of CRD-BP in the growth of human basal cell carcinoma cells.
- Immune responses in a mouse model of vitiligo with spontaneous epidermal de- and repigmentation.
- MAGE proteins regulate KRAB zinc finger transcription factors and KAP1 E3 ligase activity.
- Integrating virtual dermatopathology as part of formative and summative assessment of residents: a feasibility pilot study.
- Upregulation of PI3K/AKT/mTOR, FABP5 and PPARβ/δ in Human Psoriasis and Imiquimod-induced Murine Psoriasiform Dermatitis Model.
- Correspondence: The association between morphea profunda and monoclonal gammopathy: A case series.
- Primary cutaneous adenosquamous carcinoma of the penis: the first characterization of HPV status in this rare and diagnostically challenging entity with review of glandular carcinomas of the penis.
- TNF inhibitor induced alopecia: an unusual form of psoriasiform alopecia that breaks the Renbök mold.
- EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
- Lepromin stimulates interleukin-2 production and interleukin-2 receptor expression in situ in lepromatous leprosy patients.
- Restoration of differentiation and suppression of tumorigenicity in somatic cell hybrids of human squamous carcinoma cells and keratinocytes.
- Papilloma formation in human foreskin xenografts after inoculation of human papillomavirus type 16 DNA.
- Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection.
- Multiple tumors of the follicular infundibulum.
- Chronically KIT-stimulated clonally-derived human mast cells show heterogeneity in different tissue microenvironments.
- Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection.
- Murine cutaneous mastocytosis and epidermal melanocytosis induced by keratinocyte expression of transgenic stem cell factor.
- c-kit mutation and osteopetrosis-like osteopathy in a patient with systemic mast cell disease.
- Genital variant of folliculosebaceous cystic hamartoma.
- Columbia-Presby Med Ctr
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