Dr. Thomas John Baranski MD
Endocrinology-Diabetes | Endocrinology, Diabetes & Metabolism4570 Childrens Pl Saint Louis MO, 63110
Dr. Thomas Baranski practices Endocrinology in Saint Louis, MO. Dr. Baranski specializes in preventing, diagnosing, and treating diseases related to hormone imbalance, and the bodys glands in the endocrine system. Endocrinologists are trained and certified to treat a variety of conditions, including menopause, diabetes, infertility, and thyroid disorders, among many others. Dr. Baranski examines patients, determines means of testing, diagnoses, and decides the best treatment methods.
Education and Training
Washington Univ Sch Of Med- St Louis Mo 1992
- C5a receptor activation. Genetic identification of critical residues in four transmembrane helices.
- Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation.
- Genetic mapping of the human C5a receptor. Identification of transmembrane amino acids critical for receptor function.
- Functional reconstitution of the angiotensin II type 2 receptor and G(i) activation.
- An activation switch in the ligand binding pocket of the C5a receptor.
- Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor.
- C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast.
- C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor.
- Lysosomal enzyme phosphorylation. I. Protein recognition determinants in both lobes of procathepsin D mediate its interaction with UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase.
- Lysosomal enzyme phosphorylation. II. Protein recognition determinants in either lobe of procathepsin D are sufficient for phosphorylation of both the amino and carboxyl lobe oligosaccharides.
- Essential role for the second extracellular loop in C5a receptor activation.
- Motion of carboxyl terminus of Galpha is restricted upon G protein activation. A solution NMR study using semisynthetic Galpha subunits.
- Expressed protein ligation to study protein interactions: semi-synthesis of the G-protein alpha subunit.
- Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop.
- Mapping and molecular modeling of a recognition domain for lysosomal enzyme targeting.
- Comparison of the retinitis pigmentosa mutations in rhodopsin with a functional map of the C5a receptor.
- Random mutagenesis of the complement factor 5a (C5a) receptor N terminus provides a structural constraint for C5a docking.
- A comprehensive structure-function map of the intracellular surface of the human C5a receptor. II. Elucidation of G protein specificity determinants.
- A comprehensive structure-function map of the intracellular surface of the human C5a receptor. I. Identification of critical residues.
- E2F8 is a nonreceptor activator of heterotrimeric G proteins.
- Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye.
- Beta2-chimaerin in cancer signaling: connecting cell adhesion and MAP kinase activation.
- Structure of the complement factor 5a receptor-ligand complex studied by disulfide trapping and molecular modeling.
- Conformational movement of F251 contributes to the molecular mechanism of constitutive activation in the C5a receptor.
- Modeling molecular mechanisms of binding of the anaphylatoxin C5a to the C5a receptor.
- Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence.
- Modeling the possible conformations of the extracellular loops in
- Structural models for the complex of chemotaxis inhibitory protein of Staphylococcus aureus with the C5a receptor.
- Third extracellular loop (EC3)-N terminus interaction is important for seven-transmembrane domain receptor function: implications for an activation microswitch region.
- Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit.
- Computational modeling of constitutively active mutants of GPCRs C5a receptor.
- Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor.
- Thyroid cancer: what to do after fine needle aspiration.
- Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen.
- A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila.
- Difference between restoring and predicting 3D structures of the loops in G-protein-coupled receptors by molecular modeling.
- Structural mechanisms of constitutive activation in the C5a receptors with mutations in the extracellular loops: molecular modeling study.
- A Drosophila model of high sugar diet-induced cardiomyopathy.
- Role of fat body lipogenesis in protection against the effects of caloric overload in Drosophila.
- A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX.
- Frizzled receptors signal through G proteins.
- Evidence for transgenerational metabolic programming in Drosophila.
- Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling.
- CoA protects against the deleterious effects of caloric overload in Drosophila.
- The relationship between immunity and metabolism in diet-induced insulin resistance.
- A novel mutagenesis strategy identifies distantly spaced amino acid sequences that are required for the phosphorylation of both the oligosaccharides of procathepsin D by N-acetylglucosamine 1-phosphotransferase.
- A Gsalpha mutant designed to inhibit receptor signaling through Gs.
- Univ Ca Sf Sch Of Med, Endocrinology, Diabetes & Metabolism Univ Ca Sf Sch Of Med, Internal Medicine
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Patient Experience with Dr. Baranski
- Treatment for Diabetes
Diabetes is a common disease, but it may turn extremely chronic if left untreated without taking necessary precautions. Thus, every individual needs to offer unique care towards their health. It is recommended that diabetic patients and their families increase their awareness with respect to the...
- Weight Loss Is Key To Reversing Diabetes
Type 2 diabetes is characterized by the pancreas not making enough insulin to regulate blood sugar levels. Previously, the medical community and patients believed that a pancreas that did not work properly lasted for life, but this is not the case. New studies have found that weight loss can treat...
- New Genetic Engineering May Help Diabetes Patients with Obesity
CRISPR genetic engineering has many applications in the medical field and has revolutionized the world of genetic engineering in the last few years because it allows for very specific alteration in the DNA of human, plants and lower animal forms much faster than was previously possible.What is...
- Causes and Treatment of Hypolipidemia
What is cholesterol?Cholesterol is primarily produced in the liver, which makes approximately 1,000 milligrams of cholesterol per day. However, it can also be produced by the cells lining the small intestines and also by each cell present in the body. Abnormally low cholesterol levels would mean...
- The Diabetic's Connection to Heart Disease
Many already know that diabetes has a deep connection with heart disease, but a lot aren't sure about why or how. However, according to several studies, high blood glucose levels are a key contributor to this connection. High levels of blood glucose, or sugar, will often result in damage to the...
- "Black-ish" Diabetes Diagnosis Attempts to Improve Awareness on the Disease
Despite all the existing information on diabetes, the disease still manages to mystify a significant number of people. Some individuals could also believe that their life is over if they receive a type 2 diabetes diagnosis. Similarly, third parties may also think that diabetes patients are these...
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