Dr. Thomas Daniel Palella M.D.
Rheumatologist | Rheumatology
150 N River Rd Suite 270 Des Plaines IL, 60016About
Dr. Thomas Palella is a rheumatologist practicing in Des Plaines, IL. Dr. Palella specializes in the treatment of musculoskeletal diseases and systematic autoimmune conditions that can affect the bones, muscles or bones. Eventually, if not treated, these illnesses can also impact the skin, eyes, nervous system and internal organs. Dr. Palella treats diseases similar to orthopedists but does not perform surgery. Often times, research is conducted to find potential alternatives for the patients illness.
Education and Training
Univ of Il Coll of Med, Chicago Il 1977
University of Illinois College of Medicine 1977
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Rheumatology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Motion aftereffect as a function of the contrast of sinusoidal gratings.
- Identification of distinct PRS1 mutations in two patients with X-linked phosphoribosylpyrophosphate synthetase superactivity.
- Expression of normal and variant human hypoxanthine-guanine phosphoribosyltransferase in E. coli.
- Identification of 17 independent mutations responsible for human hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency.
- Determination of the mutations responsible for the Lesch-Nyhan syndrome in 17 subjects.
- Cloning of two distinct copies of human phosphoribosylpyrophosphate synthetase cDNA.
- Quantitative changes in T cell DNA methylation occur during differentiation and ageing.
- Crossovers within a short DNA sequence indicate a long evolutionary history of the APRT*J mutation.
- Human placental adenosine kinase: purification and characterization.
- Human placental adenosine kinase: purification and characterization.
- Mutations induced at the hypoxanthine-guanine phosphoribosyltransferase locus of human T-lymphoblasts by perturbations of purine deoxyribonucleoside triphosphate pools.
- Detection of an amino acid substitution in the mutant enzyme for a special type of adenine phosphoribosyltransferase (APRT) deficiency by sequence-specific protein cleavage.
- Expression of human hypoxanthine guanine phosphoribosyltransferase mRNA in brains of mice infected with a recombinant herpes simplex virus type 1.
- Lesch-Nyhan syndrome due to a single nucleotide change in the hypoxanthine-guanine phosphoribosyltransferase gene (HPRTYale).
- Hyperuricemia and gout in cyclosporin A-treated renal transplant recipients.
Treatments
- Psoriasis
- Osteoporosis
- Arthritis
- Osteoarthritis
- Immunodeficiency
- Rotator Cuff Syndrome
- Pain
Fellowships
- University of Michigan Medical Center, Rackman Arthritis Research
- University of Michigan
- University of Michigan Hospitals and Health Centers - University of Michigan Health System
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