Dr. Douglas S Micalizzi MD, PHD
Internist
Massachusetts General Hospital 55 Fruit St. Boston MA, 02114About
Dr. Douglas Micalizzi is an internist practicing in Boston, MA. Dr. Micalizzi specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Micalizzi provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation.
- The Six1 homeoprotein induces human mammary carcinoma cells to undergo
- Epithelial-mesenchymal transition in development and cancer.
- Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression.
- Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.
- SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer.
- Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.
- A Man in His 40s With Headache, Lethargy, and Altered Mental Status.
- The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.
- Cancer metastasis through the prism of epithelial-to-mesenchymal transition in circulating tumor cells.
- A conduit to metastasis: circulating tumor cell biology.
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