Dr. Calvin B Williams MD
Rheumatologist (Pediatric) | Pediatric Rheumatology
Children's Hospital Of Wisconsin 9000 West Wisconsin Milwaukee WI, 53226Rating
3/5
About
The broad, long-term objective of research in Dr. William's laboratory is to establish the mechanisms that promote T cell development in the thymus and maintain T cell tolerance in the periphery. He h ...
Education and Training
University Calif 1991
Board Certification
DermatologyAmerican Board of DermatologyABD
Provider Details
Expert Publications
Data provided by the National Library of Medicine- A threshold for central T cell tolerance to an inducible serum protein.
- Talo-patello-scaphoid osteolysis, synovitis, and short fourth metacarpals in sisters: a new syndrome?
- Functional reprogramming of the primary immune response by T cell receptor antagonism.
- Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice.
- Regulatory T cell development in the absence of functional Foxp3.
- Regulatory T cells dynamically control the primary immune response to foreign antigen.
- Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5.
- Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression.
- The T(reg)/Th17 cell balance: a new paradigm for autoimmunity.
- A central role for induced regulatory T cells in tolerance induction in experimental colitis.
- The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression.
- Enteric defensins are essential regulators of intestinal microbial ecology.
- Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance.
- 1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis.
- Combination therapy with methotrexate and etanercept for refractory chronic recurrent multifocal osteomyelitis.
Awards
- California Foundation for Biochemical Research 1982 Summer Fellowship
- Earl C. Anthony Dissertation Fellowship, 1989 University of California, Irvine CA
- MRES Medical Scientist Student Scholarship, 1990 University of California, Irvine CA
- 1992 Vincent P. Carroll, Jr. Memorial Research Award for Outstanding Resea
- St. Louis MO 1997 Scholar of the Center for Child Health Research at Washington Univers
- March of Dimes 1998 Basil O'Connor Research Award
- 2002 D.B. and Marjorie Reinhart Chair in Rheumatology, Children's Hospital
Treatments
- Autoimmune Disorders, Systemic Lupus Erythematosus, Rheumatic Diseases
Fellowships
- Washington University School of Medicine - Ped Rheumatology 1996
- Clinical and Research Fellow in Pediatric Immunology & Rheumatology - Washington University School of Medicine - St. Louis, MO 1993
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