Dr. David M. Shepherd MD
Ophthalmologist
41935 West Twelve Mile Road Novi Michigan, 48377About
Mention in Bio: He was the only physician in Michigan to re-certify his Boards even though he was already grandfathered in.
Education and Training
University of Michigan
Univ of Mi Med Sch, Ann Arbor Mi 1972
University of Mi Med Sch 1972
Board Certification
American Board of Ophthalmology- Ophthalmology
OphthalmologyAmerican Board of OphthalmologyABO
Provider Details
Expert Publications
Data provided by the National Library of Medicine- T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD.
- Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression.
- Early consequences of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on the activation and survival of antigen-specific T cells.
- Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells.
- Toll-like receptor ligand-induced activation of murine DC2.4 cells is attenuated by Panax notoginseng.
- Echinacea purpurea extracts modulate murine dendritic cell fate and function.
- Effects of TCDD on the fate of naive dendritic cells.
- Functional and phenotypic effects of AhR activation in inflammatory dendritic cells.
- Consequences of AhR activation in steady-state dendritic cells.
- Aryl hydrocarbon receptor activation by TCDD reduces inflammation associated with Crohn's disease.
- Anti-inflammatory effects of natural product formulations on murine dendritic cells.
- Dietary ligands of the aryl hydrocarbon receptor induce anti-inflammatory and immunoregulatory effects on murine dendritic cells.
- Inhibition of TLR ligand- and interferon gamma-induced murine microglial activation by Panax notoginseng.
- Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis.
- Anti-inflammatory effects of natural product formulations on murine macrophages.
Areas of expertise and specialization
Faculty Titles & Positions
- Teaching at Sinai Hospital -
Professional Society Memberships
- American Society of Cataract and Refractive Surgery, the American Medical Association, Michigan State Medical Society, Michigan Society of Eye Physicians and Surgeons
What do you attribute your success to?
- Love of the Field, Commitment to Continuing Education
Hobbies / Sports
- Being a Private Pilot
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