Kirsten Mancogna
Physician Assistant
1530A UNION ROAD GASTONIA NC, 28054About
Kirsten Mancogna is a physician assistant practicing in GASTONIA, NC. Kirsten specializes in preventing and treating human illness and injury by providing a broad range of care under the supervision of a physician. A physician assistant's work can include physical exams, ordering and interpreting tests, performing procedures and prescribing medication. Often times, they can assist in surgery but the scope of practice can vary according to jurisdiction or health care setting.
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Expert Publications
Data provided by the National Library of Medicine- Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.
- Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor.
- Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines.
- Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 2: identification and optimisation of substituted 2,4-bis anilino pyrimidines.
- Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor.
- How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A.
- Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode.
- Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors.
- The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor
- Novel thienopyrimidine and thiazolopyrimidine kinase inhibitors with activity against Tie-2 in vitro and in vivo.
- Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKKε kinases.
- Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation.
- Structures of the human poly (ADP-ribose) glycohydrolase catalytic domain confirm catalytic mechanism and explain inhibition by ADP-HPD derivatives.
- Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis.
- Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.
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Nearest Hospitals
CAROMONT REGIONAL MEDICAL CENTERl
2525 COURT DR GASTONIA NC 28052CAROLINAS HEALTHCARE SYSTEM KINGS MOUNTAINl
706 W KING ST KINGS MOUNTAIN NC 28086CAROLINAS HEALTHCARE SYSTEM LINCOLNl
433 MCALISTER RD LINCOLNTON NC 28092