Robert Dorfman, MD

Areas of expertise and specialization

Awards

• Best Doctors in California 2023 Best in California Magazine 
• Healthcare Hero Award 2021 Jetblue 
• America's Best Doctors 2023 America's Best Doctors 

Professional Memberships

• American Academy of Cosmetic Surgery  
• American Academy of Anti-Aging Medicine  

Charities and Philanthropic Endeavors

• Face the Future Foundation
• Friends of Israel Defense Forces

What do you attribute your success to?

• Mom, Grandma, and my Support System

Favorite Place to Vacation

• Europe

Hobbies / Sports

• Skiing, Paddle Tennis, Hiking, Traveling

Favorite professional publications

• New England Journal of Medicine, Wall Street Journal

Areas of research

Dorfman R, Gupta N, Delong M, Saadat S, Roostaeian J, “Gluteal Shape Framework for Augmentation Surgery: A Systematic Review of the Literature and Proposed Novel Classification System.” Accepted for publication in Plastic and Reconstructive Surgery.

Gordon AR, Schreiber JS, Tortora SC, Ferreira S, Dorfman RG, Saadat S, Roostaeian J, Levin JB, Tepper OM, “Turning Back the Clock with Lip Lift: Quantifying Perceived Age Reduction Using Artificial Intelligence.” Facial Plastic Surgery & Aesthetic Medicine. 2021 Jul. doi: 10.1089/fpsam.2020.0560

Deeken G, Dorfman R, Delong M, Roostaeian J, “The Beauty Pandemic: An Analysis of Cosmetic and Plastic Surgery Demand in Conjunction with the COVID-19 Quarantine of 2020.” Annals of Plastic and Aesthetic Surgery. 2021 Sep; 2(1):1007-1008.

Dorfman R, Saadat S, Gupta N, Roostaeian J, Da Lio A, “The COVID-19 Pandemic and Plastic Surgery: Literature Review, Ethical Analysis, and Proposed Guidelines.” Plastic and Reconstructive Surgery. 2020 Oct; 146(4):482e-493e. doi: 10.1097/PRS.0000000000007268.

Gupta N, Dorfman R, Saadat S, Roostaeian J, “An Updated Review of Plastic Surgery-Related Hashtag Utilization on Instagram: Implications for Education and Marketing.” Aesthetic Surgery Journal Open Forum. June 2020; Volume 2, Issue 2. https://doi.org/10.1093/asjof/ojaa011.

Gupta N, Dorfman R, Saadat S, Roostaeian J, “The Plastic Surgery Influencer – Giving Payment, Receiving Payment, and Sponsorship: A Systematic Review of the Literature and Ethical Analysis.” Aesthetic Surgery Journal. 2020 May; 40(6):691-699. doi: 10.1093/asj/sjz329.

Dorfman R, Chang I, Saadat S, Roostaeian J, “Making the Subjective Objective: Machine Learning and Rhinoplasty.” Aesthetic Surgery Journal. 2020 April; 40(5):493-498. doi: 10.1093/asj/sjz259.

Zhang M, Zhou L, Wang Y, Dorfman RG, Tang D, Xu L, Pan Y, Zhou Q, Li Y, Yin Y, Zhao S, Wu J, Yu C, “Faecalibacterium prausnitzii produces butyrate to decrease c-Myc-related metabolism and Th17 differentiation by inhibiting histone deacetylase 3.” International Immunology. 2019 Jul 30; 31(8): 499-514. doi: 10.1093/intimm/dxz022.

Zhang HL, Yan HX, Zhang J, Zhai B, Wang MD, Qin CJ, Chen J, Zhou X, Dong LW, Zhao LH, Chen Y, Li XF, Zeng J, Tang L, Sun H, Huang S, Fu BG, Zeng M, Xu DN, Li WS, Dorfman RG, Liu J, “Blocking Rictor/mTORC2-dependent glutamine synthesis suppresses tumorigenic potential of tumor initiating cells upon environmental glutamine shortage.” Paper recently submitted for publication (01/2018) in Journal of Hepatology.

Qiu C, Dorfman RG, Hockney SM, Turin S, Kim JYS, “Reply: A Quantitative Analysis of Online Reviews for Abdominoplasty.” Plastic and Reconstructive Surgery. 2019 Sep 3. doi: 10.1097/PRS.0000000000006214.

Zhang M, Pan Y, Tang D, Dorfman RG, Xu L, Zhou Q, Zhou L, Wang Y, Li Y, Yin Y, Kong B, Friess H, Zhao S, Wu J, Wang L, Zou X, “Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis.” Cell Communication and Signaling. 2019 May 6; 17(1):43. doi: 10.1186/s12964-019-0357-z.

Xu L, Li Y, Zhou L, Dorfman R, Liu L, Cai R, Jiang C, Tang D, Wang Y, Zou X, Wang L, Zhang M, “SIRT3 elicited an anti-Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis.” Cancer Medicine. 2019 May; 8(5):2380-2391. doi: 10.1002/cam4.2089.

Xu L, Wang L, Zhou L, Dorfman RG, Pan Y, Tang D, Wang Y, Yin Y, Zou X, Wu J, Zhang M, “SIRT2/cMYC pathway inhibits peroxidation-related apoptosis in cholangiocarcinoma through metabolic reprogramming.” Neoplasia. 2019 May; 21(5):429-441. doi: 10.1186/s12964-019-0332-8.

Dorfman RG, Mahmood E, Ren A, Turin S, Vaca EE, Fine, NA, Schierle CF, “Google Ranking of Plastic Surgeons Values Social Media Presence over Academic Pedigree and Experience.” Aesthetic Surgery Journal. 2019 Mar 14; 39(4):447-451. doi: 10.1093/asj/sjy285.

Qiu C, Dorfman RG, Hockney SM, Turin S, Kim JYS, “A Quantitative Analysis of Online Reviews for Abdominoplasty.” Plastic and Reconstructive Surgery. 2019 Mar; 143)3): 734-742. doi: 10.1097/PRS.0000000000005320.

Zhang M, Pan Y, Dorfman RG, Zhou Q, Yin Y, Li Y, Zhou L, Huang S, Zou X, Zhao S, “Berberine suppresses hepatic glucagon signaling and inhibits gluconeogenesis by inhibiting deacetylase SIRT3.” Endocrine. 2018 Dec; 62(3):576-587. doi: 10.1007/s12020-018-1689-y.

Li Y, Zhang M, Dorfman RG, Pan Y, Zhao Z, Zhou Q, Zhou L, Wang Y, Yin Y, Shen S, Kong B, Friess H, Zhao S, Wang L, Zou X, “SIRT2 promotes the migration and invasion of gastric cancer through RAS/ERK/JNK/MMP-9 pathway by increasing PEPCK1-related metabolism.” Neoplasia. 2018 Jul; 20(7): 745-756. doi: 10.1016/j.neo.2018.03.008.

Zhou L, Zhang M, Wang Y, Dorfman RG, Liu H, Yu T, Chen X, Tang D, Xu L, Pan Y, Zhou Q, Zhou Y, Yu C, “Faecalibacterium prausnitzii produces butyrate to maintain Th17/Treg Balance and to Ameliorate Colorectal Colitis by Inhibiting Histone Deacetylase 1.” Inflamm Bowel Dis. 2018 May 23. doi: 10.1093/ibd/izy182.

Dorfman RG, Purnell C, Qiu C, Ellis MF, Basu CB, Kim JY, “Happy and Unhappy Patients: A Quantitative Analysis of Online Plastic Surgeon Reviews for Breast Augmentation.” Plastic and Reconstructive Surgery. 2018 May;141(5):663e-673e. doi:10.1097/PRS.0000000000004268.

Tang D, Xu L, Zhang M, Dorfman RG, Pan Y, Zhou Q, Zhou L, Wang Y, Li Y, Yin Y, Wang L, Zou X, “Metformin facilitates BG45-induced apoptosis by anti-warburg effect in cholangiocarcinoma.” Oncology Reports. 2018 Apr;39(4):1957-1965. doi:10.3892/or.2018.6275. Epub 2018 Feb 20.

Mahmood E, Dorfman R, Matyal R, Jones S, Mitchell J, Mahmood F, “Augmented Reality & Ultrasound Initial Experience.” Journal of Cardiothoracic and Vascular Anesthesia. 2018 Jun;32(3):1363-1367. doi: 10.1053/j.jvca.2017.12.006. Epub 2017 Dec 6.

Dorfman RG, Mioton L, Stone E, Yan W, Qiu C, Marla S, Kim JY, “The Effect of Implant Type on Nipple Position Geometry and Aesthetics following Tissue Expander Reconstruction after Nipple Sparing Mastectomy.” Aesthetic Surgery Journal. 2017 Dec 16. doi: 10.1093/asj/sjx210.

Vieira BL, Chow I, Sinno S, Dorfman RG, Hanwright P, Gutowski KA, “Is There a Limit? A Risk Assessment Model of Liposuction and Lipoaspirate Volume on Complications in Abdominoplasty.” Plastic and Reconstructive Surgery. 2017 Dec 15. doi: 10.1097/PRS.0000000000004212.

Huang S, Zhao Z, Tang D, Zhou Q, Li Y, Zhou L, Yin Y, Wang Y, Pan Y, Dorfman RG, Ling T, Zhang M, “Down-regulation of SIRT2 inhibits invasion of hepatocellular carcinoma by inhibiting energy metabolism.” Translational Oncology. 2017 December; Volume 10, Issue 6, Pages 917-927.

Fracol M, Dorfman R, Janes L, Kulkarni S, Bethke K, Hansen N, Kim J, “The Surgical Impact of E-cigarettes: A Case Report and Review of the Current Literature.” Archives of Plastic Surgery. 2017 Oct 26. doi: 10.5999/aps.2017.00087.

Qiu CS, Jordan SW, Dorfman R, Vu MM, Alghoul MS, Kim JYS, “Surgical duration impacts venous thromboembolism risk in microsurgical breast reconstruction.” Journal of Reconstructive Microsurgery. 2017 Oct 9. doi: 10.1055/s-0037-1606339.

Dorfman RG, Vaca EE, Mahmood E, Fine NA, Schierle CF, “Plastic Surgery-Related Hashtag Utilization on Instagram: Implications for Education and Marketing.” Aesthetic Surgery Journal. 2017 Aug 30. doi: 10.1093/asj/sjx120.

Dorfman RG, Vaca EE, Fine NA, Schierle CF, “The Ethics of Sharing Plastic Surgery Videos on Social Media: Systematic Literature Review, Ethical Analysis, and Proposed Guidelines.” Plastic and Reconstructive Surgery. 2017 Oct; 140(4):825-836. doi: 10.1097/PRS.0000000000003695.

Zhang M, Pan Y, Dorfman RG, Yin Y, Zhou Q, Huang S, Liu J, Zhao S, “Down-regulation of HDAC3 inhibits growth of cholangiocarcinoma by induction of apoptosis.” Oncotarget. 2017 Jul 28. doi: 10.19632/oncotarget.19660.

Yin Y, Zhang M, Dorfman RG, Li Y, Zhao Z, Zhou Q, Huang S, Zhao S, Yao Y, Zou X, “Histone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition.” Cell Death & Disease. 2017 Jun 1; 8(6): e2856. doi: 10.1038/cddis.2016.457

Khavanin N, Qiu CS, Mlodinow AS, Vu MM, Dorfman RG, Fine NA, Kim JYS, “External Validation of the Breast Reconstruction Risk Assessment Calculator.” Journal of Plastic, Reconstructive & Aesthetic Surgery. 2017 Apr 23. Pii: S1748-6815(17)30163-8. doi: 10.1016/j.bjps.2017.04.010.

Vieira BL, Dorfman R, Turin S, Gutowski KA, “Rates and predictors of readmission following body contouring procedures: an analysis of 5,100 patients from the National Surgical Quality Improvement Program Database.” Aesthetic Surgery Journal. 2017 Feb 14. doi: 10.1093/asj/sjx012.

Zhang M, Pan Y, Dorfman RG, Yin Y, Zhou Q, Huang S, Liu J, Zhao S, “Sirtinol promotes PEPCK1 degradation and inhibits gluconeogenesis by inhibiting deacetylase SIRT2.” Scientific Reports. 2017 Dec;7(1):7. doi: 10.1038/s41598-017-00035-9.

Fine N, Schierle C, Dorfman R, “Social media poses new challenges in ethics and professionalism.” Plastic Surgery News. December 2016: i8, p. 26.

Zhang HL, Li WS, Xu DN, Zheng WW, Liu Y, Chen J, Qiu ZB, Dorfman RG, Zhang J, Liu J, “Mucosa-repairing and microbiota-balancing therapeutic effect of Bacillus subtilis alleviates dextrate sulfate sodium-induced ulcerative colitis in mice.” Experimental and Therapeutic Medicine. 2016 Oct; 12(4):2554-2562. Published online on September 8, 2016. Online ISSN: 1792-1015. Print ISSN: 1792-0981.

Zhang M, Zhou Q, Dorfman RG, Huang X, Fan T, Zhang H, Zhang J, Yu C, “Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats”. BMC Gastroenterology. 2016 Jul 30; 16(1):84. doi: 10.1186/s12876-016-0500-x

Bellare A, Dorfman R, Samuel A, Thornhill TS, “J-Integral Fracture Toughness, Tearing Modulus and Tensile Properties of Vitamin E Stabilized Radiation Crosslinked UHMWPE.” Journal of the Mechanical Behavior of Biomedical Materials. 2-16 Aug; 61:493-8. doi: 10.1016/j.jmbbm.2016.03.029. Epub 2016 Apr 11.

Zhang M, Pan Y, Dorfman RG, Chen Z, Liu F, Zhou Q, Huang S, Zhang J, Yang D, Liu J, “AR-42 Induces Cell Apoptosis in Human Hepatocellular Carcinoma Cells via HDAC5 Inhibition.” Oncotarget. 2016 Mar 14. doi: 10.18632/oncotarget.8077.

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