Dr. Robert L Safirstein MD
Nephrologist (Kidney Specialist) | Nephrology
4300 W 7th St 111/Lr Little Rock AR, 72205About
Dr. Robert Safirstein is a nephrologist practicing in Little Rock, AR. Dr. Safirstein specializes in the care and treatment of the kidneys. As a nephrologist, Dr. Safirstein most typically treats conditions like kidney stones, chronic kidney disease, acute renal failure, polycystuc kidney disease, high blood pressure and more. Nephrologists are also experts on kidney transplantation and dialysis. They are usually referred to by primary care physicians for problems related to the kidneys, and while they can perform tests to diagnose kidney disorders, they do not perform surgeries.
Education and Training
Univ of Cincinnati Coll of Med, Cincinnati Oh 1969
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Expression of the polymeric immunoglobulin receptor and excretion of secretory IgA in the postischemic kidney.
- Lessons learned from ischemic and cisplatin-induced nephrotoxicity in animals.
- Cell cycle events during renal injury.
- MAPK activation determines renal epithelial cell survival during oxidative injury.
- The lack of a functional p21(WAF1/CIP1) gene ameliorates progression to chronic renal failure.
- Positive effect of the induction of p21WAF1/CIP1 on the course of ischemic acute renal failure.
- Coordination of the cell cycle is an important determinant of the syndrome of acute renal failure.
- Monocyte chemoattractant protein-1 expression correlates with monocyte infiltration in the post-ischemic kidney.
- Protection of renal cells from cisplatin toxicity by cell cycle inhibitors.
- Cell cycle regulation: repair and regeneration in acute renal failure.
- Cisplatin nephrotoxicity.
- Activation of ERK or inhibition of JNK ameliorates H(2)O(2) cytotoxicity in mouse renal proximal tubule cells.
- Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells.
- Acute renal failure: from renal physiology to the renal transcriptome.
- Identification of the functional domain of p21(WAF1/CIP1) that protects cells from cisplatin cytotoxicity.
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