Dr. Thomas A Brasitus M.D.?
Dr. Thomas A Brasitus M.D.
Gastroenterologist | Gastroenterology
1 Atwell Rd Cooperstown NY, 13326Rating
2/5
About
Dr. Thomas Brasitus is a gastroenterologist practicing in Cooperstown, NY. Dr. Brasitus specializes in the digestive system and its diseases that affect the gastrointestinal tract, which include organs from the mouth to the anus as well as liver disorders. Gastroenterology includes conditions such as hepatitis, peptic ulcer disease, colitis, nutritional problems and irritable bowel syndrome. Dr. Brasitus performs colonoscopy and endoscopy procedures and provides accurate and thorough care for patients suffering from digestive issues.
Education and Training
Jefferson Med Coll-Thos Jefferson Univ, Philadelphia Pa 1971
Sidney Kimmel Medical College at Thomas Jefferson University 1971
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Gastroenterology
Provider Details
Expert Publications
- 1,25-dihydroxyvitamin D3 and TPA activate phospholipase D in Caco-2 cells: role of PKC-alpha.
- 1,25-dihydroxyvitamin D3 but not TPA activates PLD in Caco-2 cells via pp60(c-src) and RhoA.
- Rapid effects of 1,25(OH)2 vitamin D3 on signal transduction systems in colonic cells.
- 1,25-Dihydroxyvitamin D(3) stimulates activator protein-1-dependent Caco-2 cell differentiation.
- Inhibition of O(6)-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats.
- Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1.
- A vitamin D3 analog induces a G1-phase arrest in CaCo-2 cells by inhibiting cdk2 and cdk6: roles of cyclin E, p21Waf1, and p27Kip1.
- PKC-delta inhibits anchorage-dependent and -independent growth, enhances differentiation, and increases apoptosis in CaCo-2 cells.
- Differential regulation of the expression of Na(+)/H(+) exchanger isoform NHE3 by PKC-alpha in Caco-2 cells.
- Regulation of rat ileal NHE3 by 1,25(OH)2-vitamin D3.
- Transforming growth factor-beta 1 signaling contributes to Caco-2 cell growth inhibition induced by 1,25(OH)(2)D(3).
- 1,25-dihydroxyvitamin D3 inhibits Na(+)-H+ exchange by stimulating membrane phosphoinositide turnover and increasing cytosolic calcium in CaCo-2 cells.
- Differential effect of 1,25-dihydroxycholecalciferol on phosphoinositide turnover in the antipodal plasma membranes of colonic epithelial cells.
- Effect of vitamin D status on the rapid actions of 1,25-dihydroxycholecalciferol in rat colonic membranes.
- Modulation of P-glycoprotein-mediated drug transport by alterations in lipid fluidity of rat liver canalicular membrane vesicles.
- Mushroom poisoning: the role of orthotopic liver transplantation.
- Prostate cancer metastatic to the stomach. Clinical aspects and endoscopic diagnosis.
- Differential modulation of human small intestinal brush-border membrane hemileaflet fluidity affects leucine aminopeptidase activity and transport of D-glucose and L-glutamate.
- The role of vitamin D in normal and pathologic processes in the colon.
- K-ras oncogene mutations in rat colon tumors induced by N-methyl-N-nitrosourea.
- Incidence of Harvey ras oncogene point mutations and their expression in methylbenzylnitrosamine-induced esophageal tumorigenesis.
- Elevation of cyclic AMP levels and adenylate cyclase activity in duodenal mucosa from vitamin D-deficient rats by 1alpha,25-dihydroxycholecalciferol (1alpha,25-(OH)2D3).
- Elevation of cyclic AMP levels and adenylate cyclase activity in duodenal mucosa from vitamin D-deficient rats by 1alpha,25-dihydroxycholecalciferol (1alpha,25-(OH)2D3).
- Intestinal mucosal cyclic GMP: regulation and relation to ion transport.
- Intestinal mucosal cyclic GMP: regulation and relation to ion transport.
- Correction of enhanced Na(+)-H+ exchange of rat small intestinal brush-border membranes in streptozotocin-induced diabetes by insulin or 1,25-dihydroxycholecalciferol.
- K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors: effects of supplemental dietary calcium and vitamin D deficiency.
- Myelodysplastic syndrome and pancytopenia in a patient with non-A, non-B chronic active hepatitis.
- Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat.
- Effects of calcitonin and substance P on the transport of Ca, Na and Cl across rat ileum in vitro.
- Effects of calcitonin and substance P on the transport of Ca, Na and Cl across rat ileum in vitro.
- Use of an unsaturated fatty acid auxotroph of Saccharomyces cerevisiae to modify the lipid composition and function of mitochondrial membranes.
- Mutations in the K-ras oncogene induced by 1,2-dimethylhydrazine in preneoplastic and neoplastic rat colonic mucosa.
- Down-regulation of protein kinase C activity in 1,2-dimethylhydrazine-induced rat colonic tumors.
- Characterization and modulation of rat small intestinal brush-border membrane transbilayer fluidity.
- Reversed-phase high-performance liquid chromatographic method for the measurement of polyamine oxidase activity.
- 1,25(OH)2 vitamin D3 stimulates membrane phosphoinositide turnover, activates protein kinase C, and increases cytosolic calcium in rat colonic epithelium.
- Apical plasma membrane vesicles formed from organ donor colon demonstrate Na+ and H+ conductances and Na+/H+ exchange.
- 1,2-Dimethylhydrazine-induced alterations in protein kinase C activity in the rat preneoplastic colon.
- Correction of abnormal small intestinal cytosolic protein kinase C activity in streptozotocin-induced diabetes by insulin therapy.
- Intestinal malabsorption syndromes.
- Intestinal D-glucose transport and membrane fluidity along crypt-villus axis of streptozocin-induced diabetic rats.
- 1,2-Dimethylhydrazine-induced alterations in lipid peroxidation in preneoplastic and neoplastic colonic tissues.
- Effect of polyamine oxidase inhibition on the colonic malignant transformation process induced by 1,2-dimethylhydrazine.
- Contribution of Cl(-)-OH- exchange to electroneutral NaCl absorption in rat distal colon.
- Differential stimulation of S-adenosylmethionine decarboxylase by difluoromethylornithine in the rat colon and small intestine.
- 1,2-Dimethylhydrazine-induced alterations in N1-acetylspermidine levels in rat distal colonic mucosa: effects of 2-difluoromethylornithine.
- Na+-H+ antiporter of rat colonic basolateral membrane vesicles.
- Protein-lipid interactions in human small intestinal brush-border membranes.
- Effects of dietary fish oil supplementation on membrane fluidity and enzyme activity in rat small intestine.
- Urinary excretion of N1-acetylspermidine and other acetylated and free polyamines in the 1,2-dimethylhydrazine model of experimental rat colon cancer.
- Modulation of rat distal colonic brush-border membrane Na+-H+ exchange by dexamethasone: role of lipid fluidity.
- 1,2-Dimethylhydrazine-induced alterations in Na+-H+ exchange in rat colonic brush-border membrane vesicles.
- S-adenosyl-L-methionine modulates Na+ + K+-ATPase activity in rat colonic basolateral membranes.
- 1,2-Dimethylhydrazine-induced alterations in N1-acetylspermidine levels and spermidine N1-acetyltransferase activity in rat colonic mucosa.
- Dietary triacylglycerol modulates sodium-dependent D-glucose transport, fluidity and fatty acid composition of rat small intestinal brush-border membrane.
- Premalignant alterations in rat colonic N1-acetylspermidine levels induced by 1,2-dimethylhydrazine: effects of a high corn oil dietary regimen.
- Na+-H+ exchange in rat colonic brush-border membrane vesicles.
- Regulation of Na+-H+ exchange by transmethylation reactions in rat colonic brush-border membranes.
- The role of sphingomyelin synthetase and sphingomyelinase in 1,2-dimethylhydrazine-induced lipid alterations of rat colonic plasma membranes.
- Modulation of Na+-H+ exchange by ethinyl estradiol in rat colonic brush-border membrane vesicles.
- Modulation of lipid fluidity of small- and large-intestinal antipodal membranes by Ca2+.
- Effect of hypothyroidism on the lipid composition and fluidity of rat colonic apical plasma membranes.
- Dexamethasone influences the lipid fluidity, lipid composition and
- Estrogen-induced alterations of the acidic and neutral glycosphingolipids of rat kidney.
- Dexamethasone-induced alterations in the glycosphingolipids of rat kidney.
- Actinomycotic liver abscess. Case report and literature review.
- Rat proximal small intestinal Golgi membranes: lipid composition and fluidity.
- Premalignant alterations in the glycosphingolipids of small intestinal mucosa of rats treated with 1,2-dimethylhydrazine.
- 1,2-Dimethylhydrazine-induced premalignant alterations in the S-adenosylmethionine/S-adenosylhomocysteine ratio and membrane lipid lateral diffusion of the rat distal colon.
- Dexamethasone-induced alterations in lipid composition and fluidity of rat proximal-small-intestinal brush-border membranes.
- Estrogen-induced alterations of hematoside of rat small intestinal mucosa.
- Identification and partial characterization of phospholipid methylation in rat small-intestinal brush-border membranes.
- Dexamethasone-induced alterations in the glycosphingolipids of rat proximal small-intestinal mucosa.
- Modulation of intestinal transport processes by dietary cholesterol and triacylglycerols.
- Relationship between lipid fluidity and water permeability of bovine tracheal epithelial cell apical membranes.
- Increased calcium absorption in prehypertensive spontaneously hypertensive rat. Role of serum 1,25-dihydroxyvitamin D3 levels and intestinal brush border membrane fluidity.
- Correction by 1-25-dihydroxycholecalciferol of the abnormal fluidity and lipid composition of enterocyte brush border membranes in vitamin D-deprived rats.
- 1,2-Dimethylhydrazine-induced alterations in colonic plasma membrane fluidity: restriction to the luminal region.
- Premalignant alterations in the glycosphingolipid composition of colonic epithelial cells of rats treated with 1,2-dimethylhydrazine.
- Intraluminal calcium modulates lipid dynamics of rat intestinal brush-border
- Correction of abnormal lipid fluidity and composition of rat ileal microvillus membranes in chronic streptozotocin-induced diabetes by insulin therapy.
- Parasites ana malabsorption.
- Parasites ana malabsorption.
- Glycosphingolipid patterns of fetal and adult small intestinal mucosa in the sheep.
- Synthesis of phosphatidylcholine by two distinct methyltransferases in rat colonic brush-border membranes: evidence for extrinsic and intrinsic membrane activities.
- Premalignant alterations in the lipid composition and fluidity of colonic brush border membranes of rats administered 1,2 dimethylhydrazine.
- Functional interactions of lipids and proteins in rat intestinal microvillus membranes.
- Functional interactions of lipids and proteins in rat intestinal microvillus membranes.
- Distribution of glycosphingolipids of monkey small and large intestinal mucosa.
- Distribution of glycosphingolipids and ceramide of rat small intestinal mucosa.
- Alterations in the physical state and composition of brush border membrane lipids of rat enterocytes during differentiation.
- Glycosphingolipids of fetal and adult sheep colonic mucosa.
- Regional differences in the lipid composition and fluidity of rat colonic brush-border membranes.
- The irritable bowel syndrome.
- Membrane lipids can modulate guanylate cyclase activity of rat intestinal microvillus membranes.
- Spotting and treating serious complications of pancreatic disease.
- Lipid dynamics and protein-lipid interactions in rat colonic epithelial cell basolateral membranes.
- Lipid dynamics and lipid-protein interactions in rat enterocyte basolateral and microvillus membranes.
- Lipid composition and fluidity of rat enterocyte basolateral membranes. Regional differences.
- Parasites and malabsorption.
- Cryptosporidiosis of the human small intestine: a light and electron microscopic study.
- Disseminated Strongyloides stercoralis: a fatal case eluding diagnosis.
- Cholesterol biosynthesis and modulation of membrane cholesterol and lipid dynamics in rat intestinal microvillus membranes.
- Chronic erosive gastritis: clinical, diagnostic, and pathological features in nine patients.
- Isolation of proliferative epithelial cells from the rat cecum and proximal colon.
- Thermotropic transitions in rat intestinal plasma membranes studied by differential scanning calorimetry and fluorescence polarization.
- Primary chemoprevention strategies for colorectal cancer: ursodeoxycholic acid and other agents.
- Activation of the cystic fibrosis transmembrane conductance regulator by cGMP in the human colonic cancer cell line, Caco-2.
- Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta.
- 1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a noncalcemic analogue of 1 alpha,25-dihydroxyvitamin D3, inhibits azoxymethane-induced colonic tumorigenesis.
- 1,25-Dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol 13-acetate cause differential activation of Ca(2+)-dependent and Ca(2+)-independent isoforms of protein kinase C in rat colonocytes.
- Selective preservation of protein kinase C-zeta in the chemoprevention of azoxymethane-induced colonic tumors by piroxicam.
- 1,25-Dihydroxyvitamin D3 stimulates the phosphorylation of two acidic membrane proteins of 42,000 and 48,000 daltons in rat colonocytes: an effect modulated by vitamin D status.
- The effect of bile acids and piroxicam on MHC antigen expression in rat colonocytes during colon cancer development.
- The role of protein kinase-C alpha in the activation of particulate guanylate cyclase by 1 alpha,25-dihydroxyvitamin D3 in CaCo-2 cells.
- Vitamin D status modulates rat colonic M3 muscarinic receptor characteristics and coupling to guanylate cyclase.
- Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid.
- 1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i.
- Protein kinase C mediates the calcium-induced activation of rat colonic particulate guanylate cyclase.
- Guanylin activates rat colonic particulate guanylate cyclase.
- Relationship of P-glycoprotein and carcinoembryonic antigen expression in human colon carcinoma to local invasion, DNA ploidy, and disease relapse.
- TPA causes divergent responses of Ca(2+)-dependent and Ca(2+)-independent isoforms of PKC in the nuclei of Caco-2 cells.
- Mechanisms of Na+ transport in human distal colonic apical membrane vesicles.
- 1,25-Dihydroxycholecalciferol rapidly activates rat colonic particulate guanylate cyclase via a protein kinase C-dependent mechanism.
- M3 muscarinic receptors on rat colonocytes are coupled to particulate guanylate cyclase activation.
- Characterization of the 1,25-dihydroxycholecalciferol-stimulated calcium influx pathway in CaCo-2 cells.
- Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells.
- K-ras mutations in putative preneoplastic lesions in human colon.
- Na+ transport in human proximal colonic apical membrane vesicles.
- Inactivation of rat small intestinal brush-border membrane alkaline phosphatase by oxygen free radicals.
- Characterization of phosphoinositide-specific phospholipase C in rat colonocyte membranes.
- Effect of 1,25(OH)2D3 and its analogues on membrane phosphoinositide turnover and [Ca2+]i in Caco-2 cells.
- Supplemental dietary calcium fails to alter the acute effects of 1,2-dimethylhydrazine on O6-methylguanine, O6-alkylguanine-DNA alkyltransferase and cellular proliferation in the rat colon.
- Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas.
- Protein kinase C isoforms in the chemopreventive effects of a novel vitamin D3 analogue in rat colonic tumorigenesis.
- Shrinkage activates a nonselective conductance: involvement of a Walker-motif protein and PKC.
- Transport of n-butyrate into human colonic luminal membrane vesicles.
- 1,25 dihydroxyvitamin D3 stimulates phospholipase C-gamma in rat colonocytes: role of c-Src in PLC-gamma activation.
- Protein kinase C alpha modulates growth and differentiation in Caco-2 cells.
- Decreased PKC-alpha expression increases cellular proliferation, decreases differentiation, and enhances the transformed phenotype of CaCo-2 cells.
- PKC isoforms: villains in colon cancer?
- 1,25-Dihydroxyvitamin D3 targets PKC-betaII but not PKC-alpha to the basolateral plasma membranes of rat colonocytes.
- Expression of G protein alpha subunits in normal rat colon and in azoxymethane-induced colonic neoplasms.
Treatments
- Acid Reflux
Residency
- Ny & Presby Hp-Cornell Campus, Internal Medicine; Duke Univ Med Ctr, Internal Medicine
Dr. Thomas A Brasitus M.D.'s Practice location
Practice At 1 Atwell Rd
1 Atwell Rd -Cooperstown, NY 13326Get Direction
New patients: 607-547-6522, 607-547-3760, 607-547-3909
Fax: 607-547-3917, 607-547-6915, 607-547-6325
Dr. Thomas A Brasitus M.D.'s reviews
Write ReviewPatient Experience with Dr. Brasitus
Dr. Thomas A Brasitus M.D. has a rating of 2 out of 5 stars based on the reviews from 3 patients. FindaTopDoc has aggregated the experiences from real patients to help give you more insights and information on how to choose the best Gastroenterologist in your area. These reviews do not reflect a providers level of clinical care, but are a compilation of quality indicators such as bedside manner, wait time, staff friendliness, ease of appointment, and knowledge of conditions and treatments.
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