Dr. Patricia J Sime MD
Pulmonologist | Pulmonary Disease
601 Elmwood Ave Box Med Rochester NY, 14642About
Dr. Patricia Sime practices Pulmonology in Rochester, NY. A pulmonologist is a physician who possesses specialized knowledge and skill in the diagnosis and treatment of pulmonary conditions and diseases. Dr. Sime manages patients who need life support and mechanical ventilation, and is specially trained in diseases and conditions of the chest, particularly pneumonia, asthma, tuberculosis, emphysema, and complicated chest infections.
Education and Training
Univ of Edinburgh Med Sch, Edinburgh, Scotland 1988
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Adenoviral infection inhibits allergic airways inflammation in mice.
- Transforming growth factor-beta gene transfer to the lung induces myofibroblast presence and pulmonary fibrosis.
- Adenovirus-mediated decorin gene transfer prevents TGF-beta-induced inhibition of lung morphogenesis.
- Spatial-specific TGF-beta1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung.
- Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin.
- Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung.
- Fibrosis of the lung and other tissues: new concepts in pathogenesis and treatment.
- A new direction in the pathogenesis of idiopathic pulmonary fibrosis?
- Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains.
- Titration of non-replicating adenovirus as a vector for transducing active TGF-beta1 gene expression causing inflammation and fibrogenesis in the lungs of C57BL/6 mice.
- Expression of CD154 (CD40 ligand) by human lung fibroblasts: differential regulation by IFN-gamma and IL-13, and implications for fibrosis.
- Asbestos-derived reactive oxygen species activate TGF-beta1.
- A case of steroid responsive pulmonary hyalinising granuloma: complicated by deep venous thrombosis.
- Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer.
- A novel ELISpot method for adherent cells.
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