Dr. Patricia Ann Smethurst MD
General Practitioner
1715 INDIAN WOOD CIR MAUMEE OH, 43537About
Dr. Patricia Smethurst is a general practitioner practicing in Coldwater, MI. Dr. Smethurst does not specialize in one area of medicine, however provides routine health care services. General practitioners typically have regular, even life-long patients who they provide health care services to. Dr. Smethurst provides services including physical exams, immunizations, and diagnosing and treating multiple illnesses and injuries. General practitioners typically work in private offices and clinics and have staffs of nurses and administators.
Education and Training
Oh State Univ Coll of Med, Columbus Oh 1982
Board Certification
PediatricsAmerican Board of PediatricsABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Rapid phenotyping of HPA-1a using either diabody-based hemagglutination or recombinant IgG1-based assays.
- Threonine-145/methionine-145 variants of baculovirus produced recombinant ligand binding domain of GPIbalpha express HPA-2 epitopes and show equal binding of von Willebrand factor.
- A rapid one-stage whole-blood HPA-1a phenotyping assay using a recombinant monoclonal IgG1 anti-HPA-1a.
- Monoclonal antibody therapies in transfusion medicine.
- Gain- and loss-of-function mutants confirm the importance of apical residues to the primary interaction of human glycoprotein VI with collagen.
- Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in-depth exon resequencing and genotyping with tag single nucleotide polymorphisms.
- Collagen-mimetic peptides mediate flow-dependent thrombus formation by high- or low-affinity binding of integrin alpha2beta1 and glycoprotein VI.
- A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder.
- Calmodulin involvement in Ca2(+)-induced insulin release from electropermeabilized islets of Langerhans.
- The use of a biotin-labelled amine to identify endogenous substrates of transglutaminase in pancreatic islets.
- Measurement of tissue transglutaminase activity in a permeabilized cell system: its regulation by Ca2+ and nucleotides.
- Identification in collagen type I of an integrin alpha2 beta1-binding site containing an essential GER sequence.
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