Dr. Amyn Aziz Habib MD
Neurologist | Neurology
5323 Harry Hines Blvd Dallas TX, 75390Rating
3/5
About
I am interested in the diagnosis and treatment of brain tumors. I am also involved in basic scientific research trying to understand the biology of brain tumors and trying to identify ways to treat pa ...
Education and Training
Dow Med College University Of Karachi Pakistan 1986
Dow Med College University Of Karachi Pakistan
Board Certification
Psychiatry and NeurologyAmerican Board of Psychiatry and NeurologyABPN
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination.
- Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells.
- Oligodendrocytes regulate formation of nodes of Ranvier via the recognition molecule OMgp.
- SNS-032 prevents tumor cell-induced angiogenesis by inhibiting vascular endothelial growth factor.
- The death domain-containing kinase RIP1 regulates p27(Kip1) levels through the PI3K-Akt-forkhead pathway.
- The small-molecule CDK inhibitor, SNS-032, enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung cancer cells.
- SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1alpha expression.
- The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma.
- RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
- The receptor interacting protein 1 mediates a link between NFkappaB and PI3-kinase signaling.
- Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice.
- Downregulation of human DAB2IP gene expression in prostate cancer cells results in resistance to ionizing radiation.
- Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance.
- Improved protein arrays for quantitative systems analysis of the dynamics of signaling pathway interactions.
- Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.
Awards
- Clinical Investigator Award - National Cancer Institute 1999
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