Dr. J. Marc Pipas M.D.
Hematologist-Oncologist | Hematology & Oncology
1 Medical Center Dr Department Of Hemato Lebanon NH, 03756About
Dr. J. Pipas is a hematologist oncologist practicing in Lebanon, NH. Dr. Pipas specializes in the diagnosis, treatment and prevention of blood diseases such as anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. Hematologist Oncologists are also trained in the study of cancer and its attack on other organs.
Education and Training
Upstate Medical University/ College of Health Professions 1989
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Simian virus 40 large T antigen J domain and Rb-binding motif are sufficient to block apoptosis induced by growth factor withdrawal in a neural stem cell line.
- Expression of SV40 large T antigen in baculovirus systems and purification by immunoaffinity chromatography.
- Method for predicting RNA secondary structure.
- Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40.
- The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism.
- Loss of E2F4 activity leads to abnormal development of multiple cellular lineages.
- ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation.
- Propagation of wild-type and mutant SV40.
- Role of T antigen interactions with p53 in tumorigenesis.
- Treatment of progressive metastatic glomus jugulare tumor (paraganglioma) with gemcitabine.
- Inhibition of Rb and p53 is insufficient for SV40 T-antigen transformation.
- The virus-chaperone connection.
- Transforming functions of Simian Virus 40.
- Simian virus 40 mutants with amino-acid substitutions near the amino terminus of large T antigen.
- T-antigen mutant activities in vivo: roles of p53 and pRB binding in tumorigenesis of the choroid plexus.
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