Dr. Richard J Roller M.D.
Gastroenterologist | Gastroenterology
7000 W Colfax Ave Suite B Denver CO, 80214About
Dr. Richard Roller is a gastroenterologist practicing in Denver, CO. Dr. Roller specializes in the digestive system and its diseases that affect the gastrointestinal tract, which include organs from the mouth to the anus as well as liver disorders. Gastroenterology includes conditions such as hepatitis, peptic ulcer disease, colitis, nutritional problems and irritable bowel syndrome. Dr. Roller performs colonoscopy and endoscopy procedures and provides accurate and thorough care for patients suffering from digestive issues.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Ultrastructural localization of the herpes simplex virus type 1 UL31, UL34, and US3 proteins suggests specific roles in primary envelopment and egress of nucleocapsids.
- Effects of charged cluster mutations on the function of herpes simplex virus type
- Herpes simplex virus type 1 primary envelopment: UL34 protein modification and the US3-UL34 catalytic relationship.
- The HSV-1 Us3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members.
- Roles for herpes simplex virus type 1 UL34 and US3 proteins in disrupting the nuclear lamina during herpes simplex virus type 1 egress.
- Emerin is hyperphosphorylated and redistributed in herpes simplex virus type 1-infected cells in a manner dependent on both UL34 and US3.
- Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase.
- Analysis of a charge cluster mutation of herpes simplex virus type 1 UL34 and its extragenic suppressor suggests a novel interaction between pUL34 and pUL31 that is necessary for membrane curvature around capsids.
- Significance of host cell kinases in herpes simplex virus type 1 egress and lamin-associated protein disassembly from the nuclear lamina.
- Herpes simplex virus 1 pUL34 plays a critical role in cell-to-cell spread of virus in addition to its role in virus replication.
- A functional role for TorsinA in herpes simplex virus 1 nuclear egress.
- Intragenic and extragenic suppression of a mutation in herpes simplex virus 1 UL34 that affects both nuclear envelope targeting and membrane budding.
- Bone marrow stromal cell antigen 2 (BST-2) restricts mouse mammary tumor virus (MMTV) replication in vivo.
- BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1).
- The herpes simplex virus 1 UL51 gene product has cell type-specific functions in cell-to-cell spread.
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