Dr. John T Isaacs D.M.D.
Dentist | General Practice
39 Bobolink Dr Springfield KY, 40069About
Dr. John Isaacs is a Dentist practicing in Springfield, KY. Dr. Isaacs specializes in preventing, diagnosing, and treating diseases and conditions associated with the mouth and overall dental health. Dentists are trained to carry out such treatment as professional cleaning, restorative, prosthodontic, and endodontic procedures, and performing examinations, among many others.
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Expert Publications
Data provided by the National Library of Medicine- Assessment and validation of a microinjection method for kinetic analysis of [Ca2+]i in individual cells undergoing apoptosis.
- Rapid in situ hybridization technique for detecting malignant mouse cell contamination in human xenograft tissue from nude mice and in vitro cultures from such xenografts.
- Alpha 1-adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia.
- Inhibition of caspase activity does not prevent the signaling phase of apoptosis in prostate cancer cells.
- Methylation of the CD44 metastasis suppressor gene in human prostate cancer.
- Sustained in vivo regression of Dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555).
- The biology of hormone refractory prostate cancer. Why does it develop?
- Glyceraldehyde-3-phosphate dehydrogenase expression during apoptosis and proliferation of rat ventral prostate.
- Thapsigargin analogues for targeting programmed death of androgen-independent prostate cancer cells.
- Enhanced GBX2 expression stimulates growth of human prostate cancer cells via transcriptional up-regulation of the interleukin 6 gene.
- Thapsigargin induces a calmodulin/calcineurin-dependent apoptotic cascade responsible for the death of prostatic cancer cells.
- Apoptosis: translating theory to therapy for prostate cancer.
- Rational basis for Trk inhibition therapy for prostate cancer.
- Prostate-specific membrane antigen (PSMA) enzyme activity is elevated in prostate cancer cells.
- Mapping of metastasis suppressor genes for prostate cancer by microcell-mediated chromosome transfer.
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