John M Harlan
Hematologist-Oncologist | Hematology & Oncology
Harborview Medical Center 325 9th Ave Seattle WA, 98104About
Dr. John Harlan is a hematologist oncologist practicing in Seattle, WA. Dr. Harlan specializes in the diagnosis, treatment and prevention of blood diseases such as anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. Hematologist Oncologists are also trained in the study of cancer and its attack on other organs.
Education and Training
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med 1973
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Divergence of bacterial lipopolysaccharide pro-apoptotic signaling downstream of IRAK-1.
- The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta.
- Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells.
- Leukocyte-endothelial interactions: clinical trials of anti-adhesion therapy.
- TIRAP mediates endotoxin-induced NF-kappaB activation and apoptosis in endothelial cells.
- The GTPase Rap1 regulates phorbol 12-myristate 13-acetate-stimulated but not ligand-induced beta 1 integrin-dependent leukocyte adhesion.
- Shiga-like toxin inhibition of FLICE-like inhibitory protein expression sensitizes endothelial cells to bacterial lipopolysaccharide-induced apoptosis.
- Requirement for RhoA kinase activation in leukocyte de-adhesion.
- A broad-spectrum caspase inhibitor attenuates allergic airway inflammation in murine asthma model.
- Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
- Shiga toxin induces decreased expression of the anti-apoptotic protein Mcl-1 concomitant with the onset of endothelial apoptosis.
- Trafficking of Th1 cells to lung: a role for selectins and a P-selectin glycoprotein-1-independent ligand.
- Over-expression of Bcl-2 provides protection in septic mice by a trans effect.
- Fibroblast and endothelial apoptosis in systemic sclerosis.
- FLICE-like inhibitory protein (FLIP) protects against apoptosis and suppresses NF-kappaB activation induced by bacterial lipopolysaccharide.
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