Dr. Colin A Sieff MB, BCH
Hematologist (Pediatric) | Pediatric Hematology-Oncology
300 Longwood Ave Fegan 7 Boston MA, 02115Rating
5/5
About
Dr. Colin Sieff is a pediatric hematologist practicing in Boston, MA. Dr. Sieff specializes in treating children that have a blood disease or cancer. Such blood diseases include disorders of red blood cells, white blood cells and/or platelets. The types of cancers that Dr. Sieff treats include leukemias, lymphomas and certain tumors. Dr. Sieff can also treat bleeding disorders in children. Pediatric hematologists can be found in childrens hospitals, community hospitals, university medical centers and more.
Education and Training
University of The Witwatersrand, Faculty of Health Sciences,Parktown, South Africa 1968
Provider Details
Expert Publications
Data provided by the National Library of Medicine- One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus.
- Pure red-cell aplasia.
- Essential role for the p55 tumor necrosis factor receptor in regulating hematopoiesis at a stem cell level.
- Diamond-Blackfan anemia.
- Maturation and lineage-specific expression of the coxsackie and adenovirus receptor in hematopoietic cells.
- Evidence for linkage of familial Diamond-Blackfan anemia to chromosome 8p23.3-p22 and for non-19q non-8p disease.
- RNA and protein evidence for haplo-insufficiency in Diamond-Blackfan anaemia patients with RPS19 mutations.
- Accumulation of an intron-retained mRNA for granulocyte macrophage-colony stimulating factor receptor common beta chain in neutrophils of myelodysplastic syndromes.
- An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray.
- Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia.
- Recent insights into the pathogenesis of Diamond-Blackfan anaemia.
- A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain.
- Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia.
- Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia.
- New hats for hematopoietic hormones.
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Practice At 300 Longwood Ave Fegan 7
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Nearest Hospitals
BRIGHAM AND WOMEN'S HOSPITALl
75 FRANCIS STREET BOSTON MA 2115