expert type icon EXPERT

Dr. Kwame Anyane-yeboa, M.D.

Geneticist

Dr. Kwame Anyane-yeboa practices Genetic Medicine in New York, NY. As a geneticist, Dr. Anyane-yeboa performs experiments and analyzes data to interpret the inheritance of different traits in patients. A geneticist evaluates, diagnoses, and manages patients with hereditary conditions or congenital malformations, genetic risk calculations, and mutation analysis. Dr. Anyane-yeboa carries out studies, tests, and counsels patients with genetic diseases.
47 years Experience
Dr. Kwame Anyane-yeboa, M.D.
  • New York, NY
  • University of Ghana / Medical School
  • Accepting new patients

How accurate are DNA kits like 23andMe?

Good for Ancestry determination. Not for health related issues.

What are the various factors that cause cystic fibrosis?

Most frequent symptoms of CF are recurrent pulmonary and sinus infections. There are over 1800 genetic mutations in the CF gene. Severity of condition depends on which 2 mutations READ MORE
Most frequent symptoms of CF are recurrent pulmonary and sinus infections. There are over 1800 genetic mutations in the CF gene. Severity of condition depends on which 2 mutations are passed to that individual. An individual with CF inherits 1 copy of the mutation from each parent. Late detection suggests that the mutations are most likely mutations that cause mild disease. Mutations can be detected by genetic testing.

Is 23andMe accurate?

Ancestral history is accurate but not reliable for health information.

Is there a way to understand if my child has any genetic issue during pregnancy?

There are now non-invasive genetic tests for early pregnancy, which are done with the mother's blood. These tests are screening tests, but highly accurate to detect Down syndrome READ MORE
There are now non-invasive genetic tests for early pregnancy, which are done with the mother's blood. These tests are screening tests, but highly accurate to detect Down syndrome and some other severe chromosome abnormalities. If positive, CVS or amniocentesis can be done for confirmation.

What are the chances that my child will have sickle cell anemia?

The chance that your baby would have Sickle cell anemia is 25% (1 in 4). Sickle cell anemia can be detected in pregnancy by testing a piece of the placenta obtained through a procedure READ MORE
The chance that your baby would have Sickle cell anemia is 25% (1 in 4). Sickle cell anemia can be detected in pregnancy by testing a piece of the placenta obtained through a procedure called CVS or amniocentesis. Both procedures, although invasive, are associated with minimal risk for a miscarriage.

My son died of cystic fibrosis when he was a teenager. Is it possible for his brother to get it too?

Yes, cystic fibrosis is a very common genetic disorder. An affected individual has 2 mutations in the CF gene. Each gene is contributed from each parent. The risk that the fetus READ MORE
Yes, cystic fibrosis is a very common genetic disorder. An affected individual has 2 mutations in the CF gene. Each gene is contributed from each parent. The risk that the fetus you carry could be born with CF if from the same father is 25%. If the father is different, he needs to be tested to find out if he carries a CF mutation. Genetic testing is available in pregnancy, and can be arranged for you by your obstetrician.

Do I have to go to a geneticist for genetic testing?

Ask your physician to refer you to a genetic center for consultation with a genetic counselor who specializes in testing people at risk for cancer to determine your risk, and what READ MORE
Ask your physician to refer you to a genetic center for consultation with a genetic counselor who specializes in testing people at risk for cancer to determine your risk, and what test is available for the cancer in your family.

Can doctors identify congenital heart disease while the baby is in the womb?

Yes, most congenital heart disease can be detected with ultrasound from about 14 weeks or earlier. Note that not all heart diseases are detected in pregnancy. Mild types the involve READ MORE
Yes, most congenital heart disease can be detected with ultrasound from about 14 weeks or earlier. Note that not all heart diseases are detected in pregnancy. Mild types the involve the the septum (curtain separating the left side of the heart from the right) may sometimes be difficult to detect in pregnancy.

What conditions does gene therapy treat?

Currently gene therapy is very limited to a few conditions on research basis, however there is a lot of research going on with the technique called gene editing. This technology READ MORE
Currently gene therapy is very limited to a few conditions on research basis, however there is a lot of research going on with the technique called gene editing. This technology has potential to provide gene therapy in the future. If you are interested to know more about specific government-sponsored research for gene therapy visit www.clinicaltrials.gov.

My daughter is going for genetic testing. What should I expect?

You will first meet with a genetic counselor who will take your family history and draw a pedigree (family tree), and then see a genetics doctor who will examine you doctor and READ MORE
You will first meet with a genetic counselor who will take your family history and draw a pedigree (family tree), and then see a genetics doctor who will examine you doctor and determine the the best genetic tests available for your daughter. Sometimes genetic tests may not be indicated. Your daughter's symptoms will decide the genetic tests that should be performed.

Can leukemia be genetic?

If you brother's leukemia was not linked to a genetic disease, the risk to his child would be negligible. If linked to a genetic disorder the nature of the disorder will determine READ MORE
If you brother's leukemia was not linked to a genetic disease, the risk to his child would be negligible. If linked to a genetic disorder the nature of the disorder will determine the risk for his unborn child.

What are the causes of congenital heart diseases?

Most congenital heart disease has a hereditary component. Most parents with children born with congenital heart disease have no history of congenital heart disease, but carry READ MORE
Most congenital heart disease has a hereditary component. Most parents with children born with congenital heart disease have no history of congenital heart disease, but carry silent genes which can be passed to a child. Multiple mutated genes are required to cause congenital heart disease. In most cases the risk that a 2nd baby would be born with with heart disease is quite low-about 2-3% depending on the type of heart disease. Parents who were themselves born with heart disease have a much high recurrence, depending on the type of heart disease. Most heart disease is detectable in pregnancy with ultrasonography.

Can diabetes cause heart failure?

Yes, poorly controlled diabetes can cause heart failure.