Healthy Living

How Antioxidant-Enriched Multivitamins Help Cystic Fibrosis

Participation in the study required a long list of qualifications

Additional criteria required for participation in the study involved the following:

  • Documentation of 1 or more clinical features including: 2 well-characterized mutations in the cystic fibrosis transmembrane conductance regulator gene and/or sweat chloride equal to or above 60 milliequivalent by quantitative pilocarpine iontophoresis test
  • Pancreatic insufficiency documented by having a fecal elastase test
  • Weight above 30 kg (about 66 lb) at the screening visit
  • Ability to tolerate sputum induction with 3% hypertonic saline and to spit/cough up with induction
  • Ability to perform repetitive, consistent efforts in pulmonary function testing
  • Ability to swallow soft gel capsules
  • Clinical stability with no significant changes in the participant’s health status within 2 weeks prior to randomization
  • Written informed consent obtained from the participant or the participant’s legal representative