The history of cell therapy
The studies for using cell therapy started back in the 1990's, where it was first used for treating heart diseases. Earlier studies tried to implant stem cells derived from skeletal muscles during open heart surgery in patients who have suffered from myocardial infarction, but such studies were halted as they failed to produce many positive results.
Later studies were carried out with the CDC, with much better outcomes. Moreover, the following studies used percutaneous catheter-based delivery methods instead of open heart surgery. These studies demonstrated the effectiveness, but more importantly the safety of percutaneous catheter-based delivery methods. So, they opened up the possibilities of deploying CDC based stem-cell therapy on a much larger scale.