1 What is Rimso-50?

Brand: Rimso-50

Generic: Dimethyl Sulfoxide

Purified solution of Rimso-50 is approved by US-FDA for use in the symptomatic treatment of a painful bladder condition, interstitial cystitis.

This prescription-only solution is delivered to the bladder using a catheter (tube) or syringe and is allowed to stay there for 15 minutes. Then, it is eliminated through urine.

Various claims have been made on the use of dimethyl sulfoxide for various conditions such as arthritis, ulcers in scleroderma, muscle sprains and strains, bruises, skin infections, burns, wounds, and mental disorders.

But none of them have produced reproducible or measurable benefits. Industry-grade or veterinary use DMSO preparations do not have sufficient purity for human use. So, they must be avoided in humans.

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2 What to Know Before Using

Before using Rimso-50, you must know all about the risks and complications associated with it.

Consider the following factors before using this product:

Allergies: Inform your doctor about the allergies you have, such as to this medication, other medications, or to foods, dyes, or preservatives.

Pediatric: Safety and efficacy of this medicine in children have not been well documented to date.

Geriatric: Safety and efficacy of this medicine in elderly have been well documented till date.

Pregnancy: It falls under pregnancy category C for all trimesters, meaning that due to lack of sufficient studies, it’s not clear if this medication is safe for use in pregnancy.

Breastfeeding: Use only after assessing the risks and benefits.

Drug Interactions: Taking two medicines together can be harmful due to possible interactions. In other cases, even if there is a possible interaction between two medicines your doctor may advise you to take them together after adjusting the dose or issuing precautions.

Inform you doctor about your intake of any other prescription or nonprescription medicine.

Other Interactions: Taking your medicine together with certain foods or items such as alcohol or tobacco may cause undesirable interactions.

Talk to your doctor to know if using this medicine with food, alcohol, or tobacco is safe.

3 Proper Usage

To use Rimso-50 properly, you must follow all instructions given by your doctor. The doses of a medicine can differ according to the conditions for which it is being prescribed. Remember your doses can differ. Consult your doctor if you have anything to ask.

The doses of irrigation solution for interstitial cystitis of bladder are:

Adults: Administer 50 mL (milliliters) of a 50% solution into the bladder using a catheter and allow to stay there for 15 minutes.

Repeat the treatment every 14 days until symptoms of relief become evident, then evaluate the condition and modify the frequency of administration accordingly.

Children: Your doctor will decide the use and dose.

4 Precautions to Take

In using Rimso-50, you must be careful and take some precautions as advised by your doctor. During the use of this medicine, you need regular eye check-ups by an ophthalmologist (eye specialist).

5 Potential Side Effects

Make sure you meet with your doctor in using Rimso-50 to avoid unwanted potential side effects.

Call your doctor immediately if any of these side effects persist or worsen:

  • Bladder discomfort, which is usually self-limiting and becomes less prominent after each treatment.
  • Garlic-like taste that develops within some minutes after administration of DMSO into the bladder. This taste alteration usually takes several hours to get away.
  • Garlic-like odor of the breath and skin, which generally goes away after 72 hours.

The side effects of the medicine are not limited to the ones listed above. Call your doctor immediately if you experience any side effects that are uncommon or worry you. To report side effects to the FDA, contact at 1-800-FDA-1088.

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