1 What is Urex?

Brand: Urex, Hiprex, Mandelamine

Generic: Methenamine

Urex is an antibiotic drug, used to treat infection in the urinary tract and in the bladder by destroying the bacteria.

Read your medication guide and follow your doctor’s prescription at all times.

  • Take Urex orally/ by mouth after meals or with food per doctor’s prescription.
  • The dosage depends on your medical condition or treatment response. Do not adjust your dose without your doctor’s recommendation.
  • Do not break, chew or crush sustained- release preparation of Urex to prevent releasing the content of this medication all at once, which may intensify side effects.
  • Use a standard medicine cup/ spoon (not household spoon) to obtain the accurate amount for each dose if you are using the liquid preparation of this medication and shake the bottle well before use for liquid suspension.
  • Increase your fluid intake and/ or take in some fruit juices (i.e. cranberry, plum, prune) and more protein- rich foods for proper hydration and adequate acidity of the urine.
  • Avoid intake of antacids, citrus fruits/juices (i.e. orange, grapefruit, lemon), milk and other dairy products during your Urex treatment.
  • Continue taking Urex on a regular schedule (same time of the day). Do not stop taking this medication abruptly without consulting your doctor.

Inform your doctor immediately if your condition aggravates or does not improve.

Take your missed dose as soon as possible. However, make sure that the time interval between the missed and the next dose is not too close. Otherwise, stick with the regular schedule and leave out the missed dose. Do not double dose to cover up a missed dose. Record your missed dose and inform your doctor immediately if you missed several doses.

Urex may interact with:

  • Carbonic anhydrase inhibitor drugs (i.e. acetazolamide, methazolamide)
  • Water pill or diuretics
  • Antacids, vitamins, minerals, urinary alkalinizes and other products that contain aluminum, calcium, citric acid, magnesium, potassium, sodium bicarbonate, and sodium citrate

Some drugs may either lessen the beneficial effects or worsen the side effects of Urex. Likewise, Urex may make some drugs less efficient or intensify their side effects.

Make sure to inform your doctor about all other drugs you are currently taking or using (prescribed and non-prescribed medications including vitamins, minerals, and herbal products) to check for possible drug interaction with Urex.

Never alter the doses of other medications while on Urex neither stop nor start any medicine without the doctor’s recommendation.

Side Effects: There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling

Before taking Urex, tell your health care provider if you have/are:

  • Any allergies to any substance, food or medication, particularly to methenamine (Urex)
  • Medical history or a present condition such as:
    • Liver disease
    • Kidney problems
    • Other medical conditions
    • Taking other medications
  • Pregnant, planning to get pregnant or currently breastfeeding a baby (It is not known if Urex can harm the unborn child but it can pass through breast milk that may harm the nursing child. The risks and benefits of using this medication during pregnancy must be discussed well with your doctor).