“What happens if you drink alcohol while taking antidepressants?”

This depends upon which antidepressant you're taking: there are about two dozen possibilities. As a general rule, taking an antidepressant multiplies the effect of alcohol by two. So, one drink has the effect of two; two drinks is like having four. Sometimes benzodiazepines are used to treat depression, but they don't work well. If you're taking a benzodiazepine and mix it with alcohol, you can stop breathing and die of an overdose. And consuming a lot of alcohol can interact in the same way with other medications.