Rheumatologist | Rheumatology Questions

Who has experience with RPF (Retroperitoneal Fibrosis)? Winchester Area

Recently diagnosed, after ruling out cancer. Have NT tube on right kidney and stent in uretor.

Female | 64 years old
Complaint duration: 4 months
Medications: tamsulosin
Conditions: Retroperitoneal Fibrosis

1 Answer

Retroperitoneal Fibrosis (RPF) is a pretty rare condition that causes fibrous tissue in the retroperitoneal space, which is the area behind the abdominal cavity and outside the abdominal lining. This fibrous tissue can cause compression of surrounding tissues including the ureters, blood vessels, and other organs, leading to various symptoms. Very often it's impossible to identify the exact cause of RPF, but it can be associated with certain medical conditions, such as autoimmune diseases, infections, and malignancies. Additionally, certain medications and previous surgeries have also been linked to RPF. Symptoms of RPF can vary but often include back or flank pain, leg swelling, urinary tract symptoms, and constitutional symptoms like fever and weight loss. Imaging tests, such as CT scans, and blood tests can help diagnose RPF. Treatment for RPF typically involves a combination of medications, such as corticosteroids (Prednisone) and immunosuppressants, to reduce inflammation and fibrosis. In some cases, surgery may be necessary to relieve urinary tract obstruction caused by fibrous tissue. If you suspect you may have RPF or are experiencing symptoms, it is important to consult with a healthcare professional for an accurate diagnosis and appropriate management. Hope this helps!