Dr. John P Manis M.D.
Hematologist-Oncologist | Hematology & Oncology
16 Rutland Sq Boston MA, 02118Rating
2/5
About
Dr. John Manis is a hematologist oncologist practicing in Boston, MA. Dr. Manis specializes in the diagnosis, treatment and prevention of blood diseases such as anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. Hematologist Oncologists are also trained in the study of cancer and its attack on other organs.
Education and Training
Suny-Hlth Sci Ctr At Syracuse, Coll of Med, Syracuse Ny 1988
Upstate Medical University/ College of Health Professions 1988
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus.
- Precursors of Hodgkin's disease and B-cell lymphomas.
- Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development.
- DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway.
- Mechanism and control of class-switch recombination.
- IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells.
- The function of AID in somatic mutation and class switch recombination: upstream or downstream of DNA breaks.
- Internal IgH class switch region deletions are position-independent and enhanced by AID expression.
- Elucidation of a downstream boundary of the 3' IgH regulatory region.
- Deficiencies of GM-CSF and interferon gamma link inflammation and cancer.
- Novel antibody switching defects in human patients.
- Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice.
- p63 and p73 are not required for the development and p53-dependent apoptosis of T cells.
- Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development.
- The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.
Dr. John P Manis M.D.'s Practice location
Dr. John Manis, Md
16 Rutland Sq -Boston, MA 02118Get Direction
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Nearest Hospitals
TUFTS MEDICAL CENTERl
800 WASHINGTON STREET BOSTON MA 2111