Dr. Charles A Stanley M.D.
Endocronologist (Pediatric) | Pediatric Endocrinology34th & Civic Center Blvd Children's Hospital Philadelphia PA, 19104
Charles A. Stanley, MD, is the medical director of the Congenital Hyperinsulinism Center at The Children's Hospital of Philadelphia and a professor emeritus of pediatrics at the Perelman School of Med ...
Education and Training
Univ of Va Sch of Med, Charlottesville Va 1970
University of Virginia School of Medicine 1970
Internal MedicineAmerican Board of Internal MedicineABIM
PediatricsAmerican Board of PediatricsABP
Expert PublicationsData provided by the National Library of Medicine
- Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.
- The structure of apo human glutamate dehydrogenase details subunit communication and allostery.
- Advances in diagnosis and treatment of hyperinsulinism in infants and children.
- Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets.
- Glutaminolysis and insulin secretion: from bedside to bench and back.
- Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation.
- Clinical and molecular characterization of a dominant form of congenital hyperinsulinism caused by a mutation in the high-affinity sulfonylurea receptor.
- Newborn screening by tandem mass spectrometry for medium-chain Acyl-CoA dehydrogenase deficiency: a cost-effectiveness analysis.
- Histopathology of congenital hyperinsulinism: retrospective study with genotype correlations.
- A signaling role of glutamine in insulin secretion.
- Hyperinsulinism/hyperammonemia syndrome: insights into the regulatory role of glutamate dehydrogenase in ammonia metabolism.
- Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor.
- Congenital hyperinsulinism: intraoperative biopsy interpretation can direct the extent of pancreatectomy.
- Blood glucose control during selective arterial stimulation and venous sampling for localization of focal hyperinsulinism lesions in anesthetized children.
- Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation.
- Philadelphia Super Doctors 2012
- Membership Professional Organizations
- Member Lawson Wilkins Pediatric Endocrine Society
- Member American Association for the Advancement of Science
- Member American Diabetes Association
- Member American Pediatric Society
- Member Association for Glycogen Storage Disease
- Member Endocrine Society
- Member John Morgan Society, University of Pennsylvania
- Member Society for Inherited Metabolic Disorders
- Member Society for Pediatric Research
- Metabolic Diseases - The Children's Hospital of Philadelphia, Philadelphia, PA
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Patient Experience with Dr. Stanley
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Hypothyroidism is a common condition in which the thyroid gland is underactive and does not produce enough hormones. These hormones are very important in maintaining the metabolism of the body. Metabolism refers to the process by which cells produce and utilize energy from food. A reduction in the...
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