Another study discovered a relationship between Dry Eye Syndrome (DES) and fibromyalgia by examining patients for 11 years. This large study included 25,777 fibromyalgia patients and a control group of 103,108 participants.  The results showed a high incidence of DES in the fibro patients in comparison with the non-fibro group. In fact, women under the age of 49 were at a higher risk of developing DES.