1 What is Common Variable Immunodeficiency (CVID)?
Common variable immunodeficiency (CVID) is a rare immune disorder which impairs your immune system and increases susceptibility to infection.
If you have CVID, the level of antibodies in your body is low which makes you prone to recurrent infections of ear, sinuses and respiratory systems. You are also likely to develop digestive disorders, blood disorders and cancer if you have CVID.
The cause of CVID is unknown. Symptoms and severity of the disease vary widely. Typically, the signs and symptoms appear in adulthood, however, some people may experience them during childhood or adolescence.
Common Variable Immunodeficiency (CVID) can present in a various amount of symptoms, ranging from infections to skin conditions.
People with CVID experience:
Recurrent respiratory tract infections such as pneumonia, sinusitis. Recurrent infections may lead to permanently injured bronchi and cause bronchiectasis
Autoimmune diseases: Autoimmune diseases occur when your immune system mistakenly attacks your own healthy cells. Approximately one fifth of people with CVID are found to have autoimmune disorders, such as rheumatoid arthritis, vitiligo, hemolytic anemia, thrombocytopenia, neutropenia, and gastrointestinal diseases.
Malignancy: CVID increases risk of certain malignancies such as, lymphomas of B-cell.
Persistent giardiasis (diarrhea caused my microorganism called Giardia lamblia) leading to malabsorption.
Children with CVID show growth retardation.
Other signs and symptoms that are seen in the skin of people with CVID include:
Hair loss, either patches of hair or all of the hair falls out
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