1 Methylphenidate Hydrochloride: A Summary

Brand name:

Concerta, Metadate

Concerta is a drug used in the treatment of attention deficit hyperactivity disorder (ADHD). This drug is available as an extended release tablet containing 18 mg, 36 mg, 54 mg or 27 mg of methylphenidate hydrochloride.


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Concerta may interact with medications such as MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine).

Side Effects:

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

  • Allergy to methylphenidate
  • High blood pressure
  • Glaucoma
  • Heart problems (such as irregular heartbeat, heart failure, previous heart attack, problems with heart structure)
  • Family history of heart problems (such as sudden cardiac death, irregular heartbeat)
  • Mental/mood conditions (especially anxiety, tension, agitation)
  • Personal/family history of mental/mood disorders (such as bipolar disorder, depression, psychosis)
  • Personal/family history of uncontrolled muscle movements (motor tics, Tourette's syndrome)
  • Overactive thyroid (hyperthyroidism)
  • Seizure disorder
  • Throat/stomach/intestinal problems (such as narrowing/blockage)
  • Pregnancy or lactation

2 Related Clinical Trials