Triferic

Triferic is an iron-replacement drug for the maintenance of hemoglobin levels in patients with chronic kidney disease who are on dialysis. This drug requires a prescription.

Before using Triferic, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.

Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children below 18 years of age regarding the correlation of age to the effects of ferric pyrophosphate citrate have not been performed while safety and efficacy have not been established.

Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the utility of ferric pyrophosphate citrate. Adverse effects have been reported in animal studies but studies in pregnant women and animals are still inadequate.

Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

• Eltrombopag
• Minocycline
• Mycophenolic Acid
• Zinc

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Proper usage of Triferic requires strict adherence to your doctor’s orders. A healthcare professional will be the only one allowed to give you this drug in a dialysis clinic or hospital. This drug is added to the dialysis solution.

Before using Triferic, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness and unwanted effects of the drug. Unwanted effects can be screened using blood tests.

Seek immediate medical attention if you experience symptoms of anaphylaxis such as:

• rash
• itching
• hoarseness
• lightheadedness
• dizziness or fainting
• trouble breathing
• trouble swallowing
• any swelling of your hands, face or mouth after you receive this drug

Make sure you meet with your doctor in using Triferic to avoid unwanted potential side effects.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

• bloating or swelling of the face, arms, hands, lower legs or feet
• blurred vision
• chest pain
• confusion
• difficult or labored breathing
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fever
• rapid weight gain
• sweating
• tightness in the chest
• tingling of the hands or feet
• unusual tiredness or weakness
• unusual weight gains or loss
• bluish color of the fingernails, lips, skin, palms or nail beds
• chest discomfort
• cough
• decreased urine output
• the difficulty with swallowing
• dilated neck veins
• dizziness
• extreme fatigue
• fainting, fast, pounding, or irregular heartbeat or pulse
• hives, itching, or skin rash
• irregular breathing
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet or sex organs
• loss of consciousness, nausea or vomiting
• no blood pressure or pulse
• pain in the shoulders, arms, jaw or neck
• puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
• stopping of the heart
• swelling of the face, fingers, feet,or lower legs
• unconsciousness
• unresponsiveness
• weight gain

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.