A treatment which involves altering the genes inside your body’s cell to stop the disease is called gene therapy.
Our genes contain our DNA which is the one that controls your body’s function and forms from regulating your body systems to making you grow taller.
Diseases can re a result of genes that does not work properly. To improve your body’s ability to fight disease or in an attempt to cure disease, gene therapy will replace a faulty gene or will add a new gene.
Here are the most common reasons to undergo a gene therapy.
In order to help your body better fight disease or to cure a disease, gene therapy will be used to correct defective genes.
Researchers are investigating several ways to do this such as:
Fixing mutated genes – healthy genes that prevent disease can be turned on to inhibit the disease or mutated genes that cause disease will be turned off.
Replacing mutated genes – this may help treat certain disease because certain genes no longer work at all, for example, a gene called p5 normally prevents tumor growth in your body but if doctors can replace this defective gene it may trigger the cancer cells to die
.Making diseased cells more evident to the immune system – some of the diseased cells will not be attacked by your immune system because it does not see them as intruders, your doctors will use this therapy to train your immune system to recognize the cells that are a threat.
3 Potential Risks
Gene therapy has some possible risks. A carrier called the vector has to deliver the gene because genes cannot be directly inserted into your cells.
The most common vectors are viruses because they can recognize certain cells and carry genetic material into the gene cells.
Some of the possible risks include:
unwanted immune system reaction – this may cause inflammation or organ failure because the newly introduced viruses will see as intruders by your immune system
targeting the wrong cells – this can cause illness or disease even if cancer because viruses can affect more than one type of cells which can lead to the altered viruses infecting additional cells
infection caused by the virus – the viruses may recover their original ability to cause disease
the possibility of causing a tumor – is the new genes are inserted in the wrong spot in your DNA
To ensure the safety of those who are participating in the studies, the Food and Drug Administration and the National Institutes of Health are closely monitoring the clinical trials under way in the U.S.
4 Preparing for your Procedure
Required preparation for your gene therapy includes:
your doctor must find the faulty gene that causes a specific condition to identify it
he will locate the affected cells in the body’s organs or tissues
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